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    gtf3c4 general transcription factor IIIC, polypeptide 4 [ Danio rerio (zebrafish) ]

    Gene ID: 568510, updated on 4-Jan-2025

    Summary

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    Official Symbol
    gtf3c4provided by ZNC
    Official Full Name
    general transcription factor IIIC, polypeptide 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041008-147
    See related
    Ensembl:ENSDARG00000069538 AllianceGenome:ZFIN:ZDB-GENE-041008-147
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7138272; si:dkeyp-10e10.3
    Summary
    Predicted to enable histone acetyltransferase activity. Predicted to act upstream of or within transcription initiation at RNA polymerase III promoter. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C4 (general transcription factor IIIC subunit 4). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See gtf3c4 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17413613..17424685, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (17376852..17388164, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene TSC complex subunit 1b Neighboring gene uncharacterized LOC137488863 Neighboring gene BarH-like homeobox 1b Neighboring gene stomatin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes. Fellous A, et al. Gene, 2019 Apr 5. PMID 30615915
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within transcription initiation at RNA polymerase III promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription factor TFIIIC complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    general transcription factor 3C polypeptide 4
    XP_021329082.1
    XP_696935.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      17413613..17424685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_691843.9 → XP_696935.1  general transcription factor 3C polypeptide 4

      UniProtKB/TrEMBL
      A0A8N7TDX7
      Related
      ENSDARP00000092069.4, ENSDART00000101295.5
      Conserved Domains (2) summary
      pfam12657
      Location:48 → 234
      TFIIIC_delta; Transcription factor IIIC subunit delta N-term
      pfam12660
      Location:693 → 765
      zf-TFIIIC; Putative zinc-finger of transcription factor IIIC complex

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395085.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      118809..129808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473407.2 → XP_021329082.1  general transcription factor 3C polypeptide 4

      UniProtKB/TrEMBL
      A0A2R8RJ69, A0A8M9PDB1
      Conserved Domains (2) summary
      pfam12657
      Location:48 → 234
      TFIIIC_delta; Transcription factor IIIC subunit delta N-term
      pfam12660
      Location:693 → 765
      zf-TFIIIC; Putative zinc-finger of transcription factor IIIC complex
    Nucleotide Protein Strain
    Heading Accession and Version

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