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    sumf2 sulfatase modifying factor 2 [ Danio rerio (zebrafish) ]

    Gene ID: 449807, updated on 4-Jan-2025

    Summary

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    Official Symbol
    sumf2provided by ZNC
    Official Full Name
    sulfatase modifying factor 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-55
    See related
    Ensembl:ENSDARG00000069497 AllianceGenome:ZFIN:ZDB-GENE-041010-55
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:103574
    Summary
    Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human SUMF2 (sulfatase modifying factor 2). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See sumf2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (25669945..25676396)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (25633340..25639791)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 151A Neighboring gene transmembrane protein 179Bb Neighboring gene phosphorylase kinase, gamma 1b (muscle) Neighboring gene bicaudal-D-related protein 2-like Neighboring gene abhydrolase domain containing 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Gao S, et al. Biochim Biophys Acta Gen Subj, 2017 Mar. PMID 27773705
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inactive C-alpha-formylglycine-generating enzyme 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005980.2 → NP_001005980.1  inactive C-alpha-formylglycine-generating enzyme 2 precursor

      See identical proteins and their annotated locations for NP_001005980.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083430
      UniProtKB/TrEMBL
      A8E5E6, F6NVC3, Q5XJ75
      Related
      ENSDARP00000091977.4, ENSDART00000101203.5
      Conserved Domains (2) summary
      COG1262
      Location:25 → 287
      YfmG; Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain [Posttranslational modification, protein turnover, chaperones]
      pfam03781
      Location:25 → 287
      FGE-sulfatase; Sulfatase-modifying factor enzyme 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      25669945..25676396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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