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    zgc:55733 zgc:55733 [ Danio rerio (zebrafish) ]

    Gene ID: 393968, updated on 4-Jan-2025

    Summary

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    Official Symbol
    zgc:55733provided by ZNC
    Official Full Name
    zgc:55733provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-791
    See related
    Ensembl:ENSDARG00000103845 AllianceGenome:ZFIN:ZDB-GENE-040426-791
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    Hnrpc
    Summary
    Predicted to enable RNA binding activity. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to several human genes including HNRNPC (heterogeneous nuclear ribonucleoprotein C); HNRNPCL3 (heterogeneous nuclear ribonucleoprotein C like 3); and HNRNPCL4 (heterogeneous nuclear ribonucleoprotein C like 4). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See zgc:55733 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (4088029..4125021, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (3944121..3966557)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene spore coat protein SP96 Neighboring gene NDRG family member 2 Neighboring gene si:ch211-63p21.2 Neighboring gene si:ch211-63p21.1 Neighboring gene uncharacterized LOC101886680

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC55733

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    heterogeneous nuclear ribonucleoproteins C1/C2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200993.1 → NP_957287.1  heterogeneous nuclear ribonucleoproteins C1/C2

      See identical proteins and their annotated locations for NP_957287.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046891
      UniProtKB/TrEMBL
      Q802Y4
      Related
      ENSDARP00000134136.1, ENSDART00000167182.3
      Conserved Domains (1) summary
      cd12603
      Location:25 → 95
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      4088029..4125021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477446.2 → XP_021333121.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X5

      UniProtKB/TrEMBL
      A0A8M9QBR9
      Related
      ENSDARP00000142800.2, ENSDART00000173696.2
      Conserved Domains (1) summary
      cd12603
      Location:15 → 85
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    2. XM_021477444.2 → XP_021333119.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9Q7N2
      Conserved Domains (1) summary
      cd12603
      Location:15 → 85
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    3. XM_021477443.2 → XP_021333118.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PNP7
      Conserved Domains (1) summary
      cd12603
      Location:25 → 95
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    4. XM_021477445.2 → XP_021333120.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9QGR2
      Conserved Domains (1) summary
      cd12603
      Location:25 → 95
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    5. XM_021477442.2 → XP_021333117.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PNP7
      Conserved Domains (1) summary
      cd12603
      Location:25 → 95
      RRM_hnRNPC; RNA recognition motif in vertebrate heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNP C1/C2)

    6. XM_068222200.1 → XP_068078301.1  heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QBR5
    Nucleotide Protein Strain
    Heading Accession and Version

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