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    Igkv2-137 immunoglobulin kappa chain variable 2-137 [ Mus musculus (house mouse) ]

    Gene ID: 692187, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igkv2-137provided by MGI
    Official Full Name
    immunoglobulin kappa chain variable 2-137provided by MGI
    Primary source
    MGI:MGI:4439879
    See related
    Ensembl:ENSMUSG00000076501 IMGT/GENE-DB:IGKV2-137; AllianceGenome:MGI:4439879
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    IGKV; Gm16955
    Summary
    Acts upstream of or within response to bacterium. Predicted to be part of immunoglobulin complex. Orthologous to human IGKV2-29 (immunoglobulin kappa variable 2-29) and IGKV2D-29 (immunoglobulin kappa variable 2D-29). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Igkv2-137 in Genome Data Viewer
    Location:
    6 30.89 cM; 6 C1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (67532620..67533200)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (67555636..67556216)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_16185 Neighboring gene STARR-seq mESC enhancer starr_16186 Neighboring gene myc induced nuclear antigen pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:67483136-67483367 Neighboring gene STARR-seq mESC enhancer starr_16187 Neighboring gene immunoglobulin kappa chain variable 1-136 Neighboring gene interleukin 23 receptor Neighboring gene tumor-associated calcium signal transducer 2 Neighboring gene immunoglobulin kappa chain complex

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overpassing an aberrant V(kappa) gene to sequence an anti-idiotypic abzyme with (beta)-lactamase-like activity that could have a linkage with autoimmune diseases. Debat H, et al. FASEB J, 2001 Mar. PMID 11259400
    2. Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome. Schäble KF, et al. Eur J Immunol, 1999 Jul. PMID 10427970
    3. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
    4. IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Giudicelli V, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608191, Free PMC Article
    5. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • immunoglobulin kappa light chain

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005612.1 

      Range
      656..1236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      67532620..67533200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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