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    Dhrs1 dehydrogenase/reductase 1 [ Mus musculus (house mouse) ]

    Gene ID: 52585, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dhrs1provided by MGI
    Official Full Name
    dehydrogenase/reductase 1provided by MGI
    Primary source
    MGI:MGI:1196314
    See related
    Ensembl:ENSMUSG00000002332 AllianceGenome:MGI:1196314
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D14Ertd484e; 1110029G07Rik
    Summary
    Predicted to enable carbonyl reductase (NADPH) activity. Located in mitochondrial inner membrane. Is expressed in dorsal root ganglion; glossopharyngeal ganglion; and trigeminal ganglion. Orthologous to human DHRS1 (dehydrogenase/reductase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 54.6), testis adult (RPKM 52.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dhrs1 in Genome Data Viewer
    Location:
    14 C3; 14 28.19 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (55976477..55983147, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (55739020..55745684, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene transglutaminase 1, K polypeptide Neighboring gene STARR-seq mESC enhancer starr_36777 Neighboring gene Rab geranylgeranyl transferase, a subunit Neighboring gene STARR-positive B cell enhancer ABC_E7317 Neighboring gene STARR-positive B cell enhancer ABC_E2425 Neighboring gene NOP9 nucleolar protein Neighboring gene STARR-seq mESC enhancer starr_36778 Neighboring gene cell death-inducing DNA fragmentation factor, alpha subunit-like effector B Neighboring gene leukotriene B4 receptor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    dehydrogenase/reductase SDR family member 1
    Names
    dehydrogenase/reductase (SDR family) member 1
    short chain dehydrogenase/reductase family 19C member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026819.3NP_081095.2  dehydrogenase/reductase SDR family member 1

      See identical proteins and their annotated locations for NP_081095.2

      Status: VALIDATED

      Source sequence(s)
      AI845580, AK003958, AK159964, BU963142
      Consensus CDS
      CCDS36934.1
      UniProtKB/Swiss-Prot
      Q3THW0, Q99L04, Q9D148
      UniProtKB/TrEMBL
      Q3TVU9
      Related
      ENSMUSP00000002403.9, ENSMUST00000002403.10
      Conserved Domains (1) summary
      cd09763
      Location:5271
      DHRS1-like_SDR_c; human dehydrogenase/reductase (SDR family) member 1 (DHRS1) -like, classical (c) SDRs

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      55976477..55983147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158752.1XP_036014645.1  dehydrogenase/reductase SDR family member 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3THW0, Q99L04, Q9D148
      UniProtKB/TrEMBL
      Q3TVU9
      Conserved Domains (1) summary
      cd09763
      Location:5271
      DHRS1-like_SDR_c; human dehydrogenase/reductase (SDR family) member 1 (DHRS1) -like, classical (c) SDRs
    2. XM_030247886.1XP_030103746.1  dehydrogenase/reductase SDR family member 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3THW0, Q99L04, Q9D148
      UniProtKB/TrEMBL
      Q3TVU9
      Conserved Domains (1) summary
      cd09763
      Location:5271
      DHRS1-like_SDR_c; human dehydrogenase/reductase (SDR family) member 1 (DHRS1) -like, classical (c) SDRs