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    Etnk1 ethanolamine kinase 1 [ Mus musculus (house mouse) ]

    Gene ID: 75320, updated on 9-Dec-2024

    Summary

    Official Symbol
    Etnk1provided by MGI
    Official Full Name
    ethanolamine kinase 1provided by MGI
    Primary source
    MGI:MGI:1922570
    See related
    Ensembl:ENSMUSG00000030275 AllianceGenome:MGI:1922570
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EKI1; D6Ertd3e; 1110061E11Rik; 4930555L11Rik
    Summary
    Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including early embryo; endocrine gland; ganglia; male reproductive gland or organ; and retina. Orthologous to human ETNK1 (ethanolamine kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 42.2), CNS E18 (RPKM 41.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Etnk1 in Genome Data Viewer
    Location:
    6 G3; 6 75.41 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (143112592..143154272)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (143166866..143208546)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene C2 calcium-dependent domain containing 5 Neighboring gene STARR-positive B cell enhancer ABC_E2807 Neighboring gene STARR-seq mESC enhancer starr_17724 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:143063726-143063909 Neighboring gene predicted gene, 31108 Neighboring gene STARR-seq mESC enhancer starr_17725 Neighboring gene STARR-positive B cell enhancer ABC_E2808 Neighboring gene STARR-seq mESC enhancer starr_17731 Neighboring gene predicted gene, 38921 Neighboring gene STARR-positive B cell enhancer ABC_E2215 Neighboring gene STARR-positive B cell enhancer ABC_E2216 Neighboring gene RIKEN cDNA 1700126G02 gene Neighboring gene predicted gene, 57769 Neighboring gene RIKEN cDNA 4930407I02 gene Neighboring gene predicted gene, 52926

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ethanolamine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ethanolamine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ethanolamine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in phosphatidylethanolamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylethanolamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphatidylethanolamine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ethanolamine kinase 1
    Names
    EKI 1
    NP_083526.2
    XP_006507074.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029250.2NP_083526.2  ethanolamine kinase 1

      See identical proteins and their annotated locations for NP_083526.2

      Status: VALIDATED

      Source sequence(s)
      AK044502, AK049691, BQ175711
      Consensus CDS
      CCDS57468.1
      UniProtKB/Swiss-Prot
      F6Y9V2, Q8BXQ0, Q9D4V0
      UniProtKB/TrEMBL
      Q8BWV4
      Related
      ENSMUSP00000032413.5, ENSMUST00000032413.7
      Conserved Domains (2) summary
      PLN02236
      Location:26356
      PLN02236; choline kinase
      cd05157
      Location:49351
      ETNK_euk; Euykaryotic Ethanolamine kinase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      143112592..143154272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507011.5XP_006507074.1  ethanolamine kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A0N4SV10
      Conserved Domains (1) summary
      cd05157
      Location:49261
      ETNK_euk; Euykaryotic Ethanolamine kinase

    RNA

    1. XR_004933629.1 RNA Sequence

    2. XR_004933630.1 RNA Sequence