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    Sox5 SRY (sex determining region Y)-box 5 [ Mus musculus (house mouse) ]

    Gene ID: 20678, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sox5provided by MGI
    Official Full Name
    SRY (sex determining region Y)-box 5provided by MGI
    Primary source
    MGI:MGI:98367
    See related
    Ensembl:ENSMUSG00000041540 AllianceGenome:MGI:98367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A730017D01Rik
    Summary
    Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in cartilage condensation; chondrocyte differentiation; and positive regulation of chondrocyte differentiation. Acts upstream of or within several processes, including negative regulation of DNA-templated transcription; neurogenesis; and regulation of timing of neuron differentiation. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Orthologous to human SOX5 (SRY-box transcription factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 6.6), testis adult (RPKM 6.4) and 17 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sox5 in Genome Data Viewer
    Location:
    6 G3; 6 76.14 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (143774151..144728008, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (143828425..144782287, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31521 Neighboring gene STARR-seq mESC enhancer starr_17745 Neighboring gene predicted gene, 46720 Neighboring gene STARR-seq mESC enhancer starr_17746 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:143816722-143816875 Neighboring gene STARR-seq mESC enhancer starr_17747 Neighboring gene predicted gene, 32010 Neighboring gene predicted gene, 52486 Neighboring gene predicted gene, 52485 Neighboring gene STARR-seq mESC enhancer starr_17748 Neighboring gene STARR-seq mESC enhancer starr_17751 Neighboring gene predicted gene, 38531 Neighboring gene STARR-seq mESC enhancer starr_17756 Neighboring gene STARR-seq mESC enhancer starr_17757 Neighboring gene STARR-seq mESC enhancer starr_17758 Neighboring gene STARR-positive B cell enhancer ABC_E10417 Neighboring gene STARR-positive B cell enhancer mm9_chr6:144637695-144637995 Neighboring gene STARR-seq mESC enhancer starr_17759 Neighboring gene SRY (sex determining region Y)-box 5, opposite strand 3 Neighboring gene STARR-positive B cell enhancer mm9_chr6:144788652-144788953 Neighboring gene SRY (sex determining region Y)-box 5, opposite strand 4 Neighboring gene STARR-seq mESC enhancer starr_17760 Neighboring gene predicted gene, 32124 Neighboring gene predicted gene, 22792 Neighboring gene predicted gene, 20124

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC124352

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in asymmetric neuroblast division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cartilage condensation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cartilage development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within cartilage development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell fate commitment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cell fate commitment IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cellular response to transforming growth factor beta stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within central nervous system neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in chondrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within oligodendrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cartilage development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of chondrocyte differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of chondrocyte differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of chondrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of mesenchymal stem cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of timing of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription regulator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    transcription factor SOX-5
    Names
    SRY-box containing gene 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113559.2NP_001107031.2  transcription factor SOX-5 isoform b

      See identical proteins and their annotated locations for NP_001107031.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
      Source sequence(s)
      AC161059, AC167021, BC110478
      Consensus CDS
      CCDS51954.2
      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      UniProtKB/TrEMBL
      Q2TBA9
      Related
      ENSMUSP00000076403.6, ENSMUST00000077160.12
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    2. NM_001243163.1NP_001230092.1  transcription factor SOX-5 isoform c

      See identical proteins and their annotated locations for NP_001230092.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5_ coding region and lacks an in-frame exon in the 3_ coding region, compared to variant 1. This results in a shorter protein (isoform c), compared to isoform a.
      Source sequence(s)
      AC161059, AC167021, AK081802, BC110478
      Consensus CDS
      CCDS57469.1
      UniProtKB/TrEMBL
      B2KFM4, X2FV61
      Related
      ENSMUSP00000107378.2, ENSMUST00000111749.8
      Conserved Domains (1) summary
      cd01388
      Location:471542
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    3. NM_001347506.1NP_001334435.1  transcription factor SOX-5 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in a protein (isoform d) with a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AC167021, AK160154
      Consensus CDS
      CCDS85183.1
      UniProtKB/TrEMBL
      Q3TVF9
      Related
      ENSMUSP00000107377.2, ENSMUST00000111748.8
    4. NM_011444.3NP_035574.2  transcription factor SOX-5 isoform a

      See identical proteins and their annotated locations for NP_035574.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC161059, AC167021, AK081802, BC110478
      Consensus CDS
      CCDS39702.1
      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      UniProtKB/TrEMBL
      B2KFM9
      Related
      ENSMUSP00000047567.8, ENSMUST00000038815.14
      Conserved Domains (1) summary
      cd01388
      Location:555626
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      143774151..144728008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165995.1XP_036021888.1  transcription factor SOX-5 isoform X16

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:493564
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    2. XM_011241579.3XP_011239881.1  transcription factor SOX-5 isoform X6

      See identical proteins and their annotated locations for XP_011239881.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    3. XM_011241582.3XP_011239884.1  transcription factor SOX-5 isoform X16

      See identical proteins and their annotated locations for XP_011239884.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:493564
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    4. XM_011241577.3XP_011239879.1  transcription factor SOX-5 isoform X6

      See identical proteins and their annotated locations for XP_011239879.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    5. XM_036165997.1XP_036021890.1  transcription factor SOX-5 isoform X18

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:458529
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    6. XM_036165992.1XP_036021885.1  transcription factor SOX-5 isoform X13

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    7. XM_036165986.1XP_036021879.1  transcription factor SOX-5 isoform X12

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    8. XM_036165988.1XP_036021881.1  transcription factor SOX-5 isoform X12

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    9. XM_036165996.1XP_036021889.1  transcription factor SOX-5 isoform X18

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:458529
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    10. XM_036165991.1XP_036021884.1  transcription factor SOX-5 isoform X13

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    11. XM_011241581.3XP_011239883.1  transcription factor SOX-5 isoform X12

      See identical proteins and their annotated locations for XP_011239883.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    12. XM_036165993.1XP_036021886.1  transcription factor SOX-5 isoform X13

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    13. XM_036165987.1XP_036021880.1  transcription factor SOX-5 isoform X12

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    14. XM_011241578.3XP_011239880.1  transcription factor SOX-5 isoform X6

      See identical proteins and their annotated locations for XP_011239880.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    15. XM_006506938.5XP_006507001.1  transcription factor SOX-5 isoform X8

      See identical proteins and their annotated locations for XP_006507001.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:535606
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    16. XM_030255287.2XP_030111147.1  transcription factor SOX-5 isoform X9

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:534605
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    17. XM_006506931.5XP_006506994.1  transcription factor SOX-5 isoform X1

      See identical proteins and their annotated locations for XP_006506994.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:584655
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    18. XM_006506932.5XP_006506995.1  transcription factor SOX-5 isoform X2

      See identical proteins and their annotated locations for XP_006506995.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:583654
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    19. XM_006506942.5XP_006507005.1  transcription factor SOX-5 isoform X15

      See identical proteins and their annotated locations for XP_006507005.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:499570
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    20. XM_006506934.5XP_006506997.1  transcription factor SOX-5 isoform X4

      See identical proteins and their annotated locations for XP_006506997.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:549620
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    21. XM_006506935.5XP_006506998.1  transcription factor SOX-5 isoform X5

      See identical proteins and their annotated locations for XP_006506998.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:548619
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    22. XM_017321475.3XP_017176964.1  transcription factor SOX-5 isoform X17

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:472543
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    23. XM_030255290.2XP_030111150.1  transcription factor SOX-5 isoform X14

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      UniProtKB/TrEMBL
      E9PVR0
      Related
      ENSMUSP00000133041.3, ENSMUST00000170367.9
      Conserved Domains (1) summary
      cd01388
      Location:506577
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    24. XM_006506933.5XP_006506996.1  transcription factor SOX-5 isoform X3

      See identical proteins and their annotated locations for XP_006506996.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:556627
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    25. XM_006506939.5XP_006507002.1  transcription factor SOX-5 isoform X10

      See identical proteins and their annotated locations for XP_006507002.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:521592
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    26. XM_011241580.4XP_011239882.1  transcription factor SOX-5 isoform X11

      See identical proteins and their annotated locations for XP_011239882.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:520591
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    27. XM_036165998.1XP_036021891.1  transcription factor SOX-5 isoform X18

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:458529
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    28. XM_030255289.2XP_030111149.1  transcription factor SOX-5 isoform X13

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    29. XM_006506940.5XP_006507003.1  transcription factor SOX-5 isoform X12

      See identical proteins and their annotated locations for XP_006507003.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    30. XM_006506936.5XP_006506999.1  transcription factor SOX-5 isoform X6

      See identical proteins and their annotated locations for XP_006506999.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    31. XM_006506941.5XP_006507004.1  transcription factor SOX-5 isoform X13

      See identical proteins and their annotated locations for XP_006507004.1

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    32. XM_036165989.1XP_036021882.1  transcription factor SOX-5 isoform X12

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    33. XM_006506937.5XP_006507000.1  transcription factor SOX-5 isoform X6

      See identical proteins and their annotated locations for XP_006507000.1

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    34. XM_036165999.1XP_036021892.1  transcription factor SOX-5 isoform X18

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:458529
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    35. XM_036165985.1XP_036021878.1  transcription factor SOX-5 isoform X7

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:542613
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    36. XM_036165984.1XP_036021877.1  transcription factor SOX-5 isoform X6

      UniProtKB/Swiss-Prot
      O88184, O89018, P35710
      Conserved Domains (1) summary
      cd01388
      Location:543614
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    37. XM_036165990.1XP_036021883.1  transcription factor SOX-5 isoform X12

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:508579
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    38. XM_036165994.1XP_036021887.1  transcription factor SOX-5 isoform X13

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:507578
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    39. XM_036166000.1XP_036021893.1  transcription factor SOX-5 isoform X18

      UniProtKB/TrEMBL
      X2FV61
      Conserved Domains (1) summary
      cd01388
      Location:458529
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    40. XM_006506945.5XP_006507008.1  transcription factor SOX-5 isoform X20

      See identical proteins and their annotated locations for XP_006507008.1

      Conserved Domains (1) summary
      cd01388
      Location:233304
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    41. XM_036166001.1XP_036021894.1  transcription factor SOX-5 isoform X19

      Conserved Domains (1) summary
      cd01388
      Location:262333
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...