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    Mtres1 mitochondrial transcription rescue factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 67851, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mtres1provided by MGI
    Official Full Name
    mitochondrial transcription rescue factor 1provided by MGI
    Primary source
    MGI:MGI:1915101
    See related
    Ensembl:ENSMUSG00000019797 AllianceGenome:MGI:1915101
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700021F05Rik
    Summary
    Predicted to enable ribosomal large subunit binding activity and tRNA binding activity. Predicted to be involved in regulation of mitochondrial transcription and rescue of stalled ribosome. Located in mitochondrion. Orthologous to human MTRES1 (mitochondrial transcription rescue factor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 3.3), CNS E11.5 (RPKM 3.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mtres1 in Genome Data Viewer
    Location:
    10 B2; 10 23.01 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (43401115..43417037, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (43525119..43541041, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47889 Neighboring gene presequence translocase associated motor 16 like Neighboring gene STARR-seq mESC enhancer starr_26515 Neighboring gene STARR-positive B cell enhancer ABC_E10603 Neighboring gene STARR-positive B cell enhancer ABC_E6836 Neighboring gene STARR-positive B cell enhancer ABC_E6837 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:43301229-43301412 Neighboring gene CD24a antigen Neighboring gene RIKEN cDNA F930017D23 gene Neighboring gene predicted gene, 51800

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Reymond A, et al. Genomics, 2001 Nov. PMID 11707072
    2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
    3. Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers. Wang C, et al. FASEB J, 2019 Aug. PMID 31162944, Free PMC Article
    4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ribosomal large subunit binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ribosomal large subunit binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables tRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of mitochondrial transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitochondrial transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of mitochondrial transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in rescue of stalled ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in rescue of stalled ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial transcription rescue factor 1
    Names
    uncharacterized protein C6orf203 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026411.2 → NP_080687.1  mitochondrial transcription rescue factor 1

      See identical proteins and their annotated locations for NP_080687.1

      Status: VALIDATED

      Source sequence(s)
      AC159462, AK006199, DV045344
      Consensus CDS
      CCDS23820.1
      UniProtKB/Swiss-Prot
      Q3TQU4, Q9CQF4
      Related
      ENSMUSP00000119053.3, ENSMUST00000147196.3
      Conserved Domains (1) summary
      TIGR03069
      Location:133 → 227
      PS_II_S4; photosystem II S4 domain protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      43401115..43417037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512833.5 → XP_006512896.1  mitochondrial transcription rescue factor 1 isoform X1

      See identical proteins and their annotated locations for XP_006512896.1

      UniProtKB/Swiss-Prot
      Q3TQU4, Q9CQF4
      Conserved Domains (1) summary
      TIGR03069
      Location:133 → 227
      PS_II_S4; photosystem II S4 domain protein

    2. XM_006512834.4 → XP_006512897.1  mitochondrial transcription rescue factor 1 isoform X1

      See identical proteins and their annotated locations for XP_006512897.1

      UniProtKB/Swiss-Prot
      Q3TQU4, Q9CQF4
      Conserved Domains (1) summary
      TIGR03069
      Location:133 → 227
      PS_II_S4; photosystem II S4 domain protein

    3. XM_017314069.2 → XP_017169558.1  mitochondrial transcription rescue factor 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3TQU4, Q9CQF4
      Conserved Domains (1) summary
      TIGR03069
      Location:133 → 227
      PS_II_S4; photosystem II S4 domain protein

    4. XM_011243202.2 → XP_011241504.1  mitochondrial transcription rescue factor 1 isoform X2

      Conserved Domains (1) summary
      COG2302
      Location:131 → 186
      YlmH; RNA-binding protein YlmH, contains S4-like domain [General function prediction only]

    RNA

    1. XR_004936264.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CQF4.1 GenPept UniProtKB/Swiss-Prot:Q9CQF4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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