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    Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain1 [ Mus musculus (house mouse) ]

    Gene ID: 13196, updated on 3-Dec-2024

    Summary

    Official Symbol
    Asap1provided by MGI
    Official Full Name
    ArfGAP with SH3 domain, ankyrin repeat and PH domain1provided by MGI
    Primary source
    MGI:MGI:1342335
    See related
    Ensembl:ENSMUSG00000022377 AllianceGenome:MGI:1342335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PAP; s19; DEF-1; Ddef1; mKIAA1249
    Summary
    Enables GTPase activator activity and phospholipid binding activity. Involved in regulation of postsynapse organization. Acts upstream of or within negative regulation of dendritic spine development and positive regulation of membrane tubulation. Located in dendritic spine and podosome. Is active in glutamatergic synapse. Is expressed in several structures, including gonad; hemolymphoid system; limb; long bone; and nervous system. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 21.3), cortex adult (RPKM 15.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Asap1 in Genome Data Viewer
    Location:
    15 D1; 15 28.55 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (63958704..64254922, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (64086840..64382941, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene gasdermin C-like, pseudogene Neighboring gene CYFIP related Rac1 interactor B Neighboring gene STARR-seq mESC enhancer starr_38847 Neighboring gene STARR-seq mESC enhancer starr_38849 Neighboring gene STARR-positive B cell enhancer ABC_E10857 Neighboring gene STARR-positive B cell enhancer ABC_E9912 Neighboring gene predicted gene, 25628 Neighboring gene STARR-positive B cell enhancer ABC_E1906 Neighboring gene predicted gene 20717 Neighboring gene STARR-seq mESC enhancer starr_38853 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:64017486-64017639 Neighboring gene STARR-seq mESC enhancer starr_38854 Neighboring gene VISTA enhancer mm1716 Neighboring gene STARR-seq mESC enhancer starr_38855 Neighboring gene RIKEN cDNA 1700010G06 gene Neighboring gene STARR-seq mESC enhancer starr_38857 Neighboring gene predicted gene, 30563 Neighboring gene predicted gene, 46509

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylserine binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within negative regulation of dendritic spine development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of membrane tubulation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of membrane tubulation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of postsynapse organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of postsynapse organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in dendritic spine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in podosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in podosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
    Names
    130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
    130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
    ADP-ribosylation factor-directed GTPase-activating protein 1
    ARF GTPase-activating protein 1
    PIP2-dependent ARF1 GAP
    development and differentiation-enhancing factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001276461.2NP_001263390.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two in-frame exons in the coding region, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
      Source sequence(s)
      AC098728, AC131710, AC156573
      Consensus CDS
      CCDS70633.1
      UniProtKB/TrEMBL
      H3BKE6, Q3UJA5
      Related
      ENSMUSP00000135359.2, ENSMUST00000175799.8
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10291085
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7391018
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:328434
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:613646
      ANK; ANK repeat [structural motif]
      cd08848
      Location:449570
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:617689
      Ank_2; Ankyrin repeats (3 copies)
    2. NM_001276462.2NP_001263391.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, uses a downstream start codon, and lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
      Source sequence(s)
      AC131710, AC156573
      Consensus CDS
      CCDS70631.1
      UniProtKB/TrEMBL
      E9QN63, H3BL41
      Related
      ENSMUSP00000135643.2, ENSMUST00000177371.8
      Conserved Domains (7) summary
      cd07641
      Location:34248
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10661122
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7171055
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:308414
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:593626
      ANK; ANK repeat [structural motif]
      cd08848
      Location:429550
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:597669
      Ank_2; Ankyrin repeats (3 copies)
    3. NM_001276463.2NP_001263392.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, uses a downstream start codon, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (d) is shorter than isoform a.
      Source sequence(s)
      AC131710, AC156573
      Consensus CDS
      CCDS70632.1
      UniProtKB/TrEMBL
      E9QMJ1, E9QN63
      Related
      ENSMUSP00000134877.2, ENSMUST00000177083.8
      Conserved Domains (7) summary
      cd07641
      Location:34248
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10541110
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7051043
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:296402
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:581614
      ANK; ANK repeat [structural motif]
      cd08848
      Location:417538
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:585657
      Ank_2; Ankyrin repeats (3 copies)
    4. NM_001276467.2NP_001263396.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (e) is shorter than isoform a.
      Source sequence(s)
      AC098728, AC131710, AC156573
      Consensus CDS
      CCDS70634.1
      UniProtKB/TrEMBL
      E9QMI7
      Related
      ENSMUSP00000135190.2, ENSMUST00000176384.8
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10321088
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7421021
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:331437
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:616649
      ANK; ANK repeat [structural motif]
      cd08848
      Location:452573
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:620692
      Ank_2; Ankyrin repeats (3 copies)
    5. NM_001411185.1NP_001398114.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC098728, AC131710, AC156573
      UniProtKB/TrEMBL
      E9QN63
      Related
      ENSMUSP00000105742.3, ENSMUST00000110115.9
    6. NM_010026.4NP_034156.2  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform a

      See identical proteins and their annotated locations for NP_034156.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AC098728, AC131710, AC156573
      Consensus CDS
      CCDS56986.1
      UniProtKB/Swiss-Prot
      O08612, Q505F0, Q80TG8, Q80UV6, Q99LV8, Q9QWY8, Q9Z2B6
      UniProtKB/TrEMBL
      E9QN63
      Related
      ENSMUSP00000134825.2, ENSMUST00000177374.8
      Conserved Domains (9) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10891145
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:616704
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:331437
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:341426
      PH; PH domain
      pfam01412
      Location:454570
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:597682
      Ank_2; Ankyrin repeats (3 copies)
      pfam16638
      Location:9311013
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      sd00045
      Location:616649
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      63958704..64254922 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159121.1XP_036015014.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X14

      UniProtKB/TrEMBL
      H3BKD4, Q3UJA5
      Related
      ENSMUSP00000135346.2, ENSMUST00000177035.8
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10171073
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7271006
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:316422
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:601634
      ANK; ANK repeat [structural motif]
      cd08848
      Location:437558
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:605677
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_036159120.1XP_036015013.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      E9QMI7
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10201076
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7301009
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:319425
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:604637
      ANK; ANK repeat [structural motif]
      cd08848
      Location:440561
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:608680
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_036159117.1XP_036015010.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      E9QN63
      Related
      ENSMUSP00000135718.2, ENSMUST00000175793.8
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10771133
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7281066
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:319425
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:604637
      ANK; ANK repeat [structural motif]
      cd08848
      Location:440561
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:608680
      Ank_2; Ankyrin repeats (3 copies)
    4. XM_036159116.1XP_036015009.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      E9QN63, H3BJY2
      Related
      ENSMUSP00000135172.2, ENSMUST00000176014.8
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10861142
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7371075
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:328434
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:613646
      ANK; ANK repeat [structural motif]
      cd08848
      Location:449570
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:617689
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_036159119.1XP_036015012.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd11965
      Location:10301086
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:6811019
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:272378
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:557590
      ANK; ANK repeat [structural motif]
      cd08848
      Location:393514
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:561633
      Ank_2; Ankyrin repeats (3 copies)
      cl12013
      Location:1209
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    6. XM_006520395.2XP_006520458.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd07641
      Location:138344
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:11501206
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd13251
      Location:392498
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:677710
      ANK; ANK repeat [structural motif]
      cd08848
      Location:513634
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam03154
      Location:8301094
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:681753
      Ank_2; Ankyrin repeats (3 copies)
    7. XM_006520394.2XP_006520457.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd07641
      Location:138344
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:11531209
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd13251
      Location:395501
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:680713
      ANK; ANK repeat [structural motif]
      cd08848
      Location:516637
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam03154
      Location:8331097
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:684756
      Ank_2; Ankyrin repeats (3 copies)
    8. XM_036159115.1XP_036015008.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      Q3UJA5
      Conserved Domains (7) summary
      cd11965
      Location:11051161
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:8151094
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:404510
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:689722
      ANK; ANK repeat [structural motif]
      cd08848
      Location:525646
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:693765
      Ank_2; Ankyrin repeats (3 copies)
      cl12013
      Location:138344
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    9. XM_006520393.2XP_006520456.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd07641
      Location:138344
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:11621218
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd13251
      Location:404510
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:689722
      ANK; ANK repeat [structural motif]
      cd08848
      Location:525646
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam03154
      Location:8421106
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:693765
      Ank_2; Ankyrin repeats (3 copies)
    10. XM_006520397.2XP_006520460.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      E9QMI7
      Conserved Domains (7) summary
      cd11965
      Location:11081164
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:8181097
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:407513
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:692725
      ANK; ANK repeat [structural motif]
      cd08848
      Location:528649
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:696768
      Ank_2; Ankyrin repeats (3 copies)
      cl12013
      Location:138344
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    11. XM_006520392.2XP_006520455.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd07641
      Location:138344
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:11651221
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd13251
      Location:407513
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:692725
      ANK; ANK repeat [structural motif]
      cd08848
      Location:528649
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam03154
      Location:8451109
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:696768
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_036159118.1XP_036015011.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd07641
      Location:34248
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10691125
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      PHA03247
      Location:7201058
      PHA03247; large tegument protein UL36; Provisional
      cd13251
      Location:311417
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:596629
      ANK; ANK repeat [structural motif]
      cd08848
      Location:432553
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam12796
      Location:600672
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_011245448.1XP_011243750.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      E9QN63
      Conserved Domains (7) summary
      cd11965
      Location:10381094
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd13251
      Location:280386
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:565598
      ANK; ANK repeat [structural motif]
      cd08848
      Location:401522
      ArfGap_ASAP1; ArfGAP domain of ASAP1 (ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein 1)
      pfam03154
      Location:718982
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:569641
      Ank_2; Ankyrin repeats (3 copies)
      cl12013
      Location:12217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature