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    A2ML4 alpha-2-macroglobulin-like 4 [ Gallus gallus (chicken) ]

    Gene ID: 100858010, updated on 3-Dec-2024

    Summary

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    Official Symbol
    A2ML4provided by CGNC
    Official Full Name
    alpha-2-macroglobulin-like 4provided by CGNC
    Primary source
    CGNC:65057
    See related
    Ensembl:ENSGALG00010026205
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See A2ML4 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (1334405..1345132)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (2553378..2564073)

    Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene proline-rich protein 29-like Neighboring gene proline rich 29 Neighboring gene FtsJ homolog 3 Neighboring gene proteasome 26S subunit, ATPase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2-macroglobulin-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1334405..1345132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015299405.4 → XP_015154891.2  alpha-2-macroglobulin-like protein 1

      UniProtKB/TrEMBL
      A0A8V1AAP1, A0A8V1ACX8
      Related
      ENSGALP00010039338.1, ENSGALT00010063790.1
      Conserved Domains (2) summary
      COG2373
      Location:127 → 1282
      YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
      cd02897
      Location:968 → 1261
      A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...

    2. XM_046904384.1 → XP_046760340.1  alpha-2-macroglobulin-like protein 1

      UniProtKB/TrEMBL
      A0A8V1AAP1, A0A8V1ACX8
      Related
      ENSGALP00010039342.1, ENSGALT00010063798.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      2553378..2564073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040692068.2 → XP_040548002.1  alpha-2-macroglobulin-like protein 1

      UniProtKB/TrEMBL
      A0A8V1ACX8
      Conserved Domains (2) summary
      COG2373
      Location:127 → 1282
      YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
      cd02897
      Location:968 → 1261
      A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...

    2. XM_046933508.1 → XP_046789464.1  alpha-2-macroglobulin-like protein 1

      UniProtKB/TrEMBL
      A0A8V1ACX8
    Nucleotide Protein Strain
    Heading Accession and Version

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