LBH LBH regulator of WNT signaling pathway [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: LBHprovided by CGNC
Official Full Name: LBH regulator of WNT signaling pathwayprovided by CGNC
Primary source: CGNC:51464
See related: Ensembl:ENSGALG00010017485
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: limb-bud-and-heart
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (8278506..8289180, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (8224140..8234824, complement)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

during endochondral bone formation, Lbh may negatively regulate vascular invasion and formation of the early ossification center at least in part by interfering with Runx2 and/or VEGF expression
Title: The transcriptional cofactor Lbh regulates angiogenesis and endochondral bone formation during fetal bone development.

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein LBH

Names: limb bud and heart development homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031038.2 → NP_001026209.2 protein LBH

Status: PROVISIONAL

Source sequence(s)

JAENSK010000061

UniProtKB/Swiss-Prot

Q5ZM46

UniProtKB/TrEMBL

F1NGY2

Related

ENSGALP00010024752.1, ENSGALT00010042239.1

Conserved Domains (1) summary

pfam15317
Location:18 → 82

Lbh; Cardiac transcription factor regulator, Developmental protein

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

8278506..8289180 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)