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    LATS1 large tumor suppressor kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 421627, updated on 17-Aug-2024

    Summary

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    Symbol
    LATS1provided by CGNC
    Full Name
    large tumor suppressor kinase 1provided by CGNC
    Primary source
    CGNC:9407
    See related
    Ensembl:ENSGALG00010005504
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See LATS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (47865269..47887847, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (47766972..47789515, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene glycoprotein integral membrane 1 Neighboring gene katanin catalytic subunit A1 Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene nucleoporin 43 Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase LATS1
    Names
    LATS, large tumor suppressor, homolog 1
    XP_004935663.2
    XP_025005082.2
    XP_040522272.1
    XP_040522275.1
    XP_040522276.1
    XP_040553575.1
    XP_040553576.1
    XP_040553578.1
    XP_040553579.1
    XP_046770529.1
    XP_046770530.1
    XP_046770531.1
    XP_046770532.1
    XP_046795130.1
    XP_046795131.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      47865269..47887847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025149314.3 → XP_025005082.2  serine/threonine-protein kinase LATS1 isoform X4

      Conserved Domains (3) summary
      PRK10263
      Location:479 → 680
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:704 → 1085
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    2. XM_004935606.5 → XP_004935663.2  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6
      Related
      ENSGALP00010007725.1, ENSGALT00010013163.1
      Conserved Domains (3) summary
      PRK10263
      Location:485 → 686
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:710 → 1091
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    3. XM_046939175.1 → XP_046795131.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6

    4. XM_046939174.1 → XP_046795130.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6

    5. XM_040697645.2 → XP_040553579.1  serine/threonine-protein kinase LATS1 isoform X4

      Conserved Domains (3) summary
      PRK10263
      Location:479 → 680
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:704 → 1085
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    6. XM_040697644.2 → XP_040553578.1  serine/threonine-protein kinase LATS1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XS20
      Related
      ENSGALP00010007727.1, ENSGALT00010013165.1
      Conserved Domains (3) summary
      PRK10263
      Location:480 → 681
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:705 → 1086
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    7. XM_040697642.2 → XP_040553576.1  serine/threonine-protein kinase LATS1 isoform X2

      Conserved Domains (3) summary
      PRK10263
      Location:484 → 685
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:709 → 1090
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    8. XM_040697641.2 → XP_040553575.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6
      Conserved Domains (3) summary
      PRK10263
      Location:485 → 686
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:710 → 1091
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      47766972..47789515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040666342.2 → XP_040522276.1  serine/threonine-protein kinase LATS1 isoform X4

      Conserved Domains (3) summary
      PRK10263
      Location:479 → 680
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:704 → 1085
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    2. XM_046914576.1 → XP_046770532.1  serine/threonine-protein kinase LATS1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XS20

    3. XM_046914575.1 → XP_046770531.1  serine/threonine-protein kinase LATS1 isoform X2

    4. XM_040666338.2 → XP_040522272.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6
      Conserved Domains (3) summary
      PRK10263
      Location:485 → 686
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:710 → 1091
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1

    5. XM_046914574.1 → XP_046770530.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6

    6. XM_046914573.1 → XP_046770529.1  serine/threonine-protein kinase LATS1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XUM6

    7. XM_040666341.2 → XP_040522275.1  serine/threonine-protein kinase LATS1 isoform X4

      Conserved Domains (3) summary
      PRK10263
      Location:479 → 680
      PRK10263; DNA translocase FtsK; Provisional
      cd14397
      Location:104 → 144
      UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
      cd05625
      Location:704 → 1085
      STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
    Nucleotide Protein Strain
    Heading Accession and Version

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