RBPJ recombination signal binding protein for immunoglobulin kappa J region [Gallus gallus (chicken)] - Gene

Summary

Symbol: RBPJprovided by CGNC
Full Name: recombination signal binding protein for immunoglobulin kappa J regionprovided by CGNC
Primary source: CGNC:10692
See related: Ensembl:ENSGALG00010010837
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: RBPJk
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	4	NC_052535.1 (72747615..72891389, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	4	NC_052576.1 (72729811..72874132, complement)

Chromosome 4 - NC_052535.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the Rbpj-interacting domains of Ptf1a protein were required for its effects on retinal ganglion cell fate specification
Title: Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina.

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: recombining binding protein suppressor of hairless

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

72747615..72891389 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046940616.1 → XP_046796572.1 recombining binding protein suppressor of hairless isoform X5

UniProtKB/TrEMBL

A0A8V0Y6Q4
XM_420752.8 → XP_420752.2 recombining binding protein suppressor of hairless isoform X6

UniProtKB/TrEMBL

A0A3Q2UCS9, A0A8V0Y6L7

Related

ENSGALP00010014634.1, ENSGALT00010025973.1

Conserved Domains (3) summary

cd01176
Location:334 → 430

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:190 → 312

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:32 → 157

LAG1-DNAbind; LAG1, DNA binding
XM_046940620.1 → XP_046796576.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_046940618.1 → XP_046796574.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

Related

ENSGALP00010014629.1, ENSGALT00010025968.1
XM_046940621.1 → XP_046796577.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_015285708.4 → XP_015141194.1 recombining binding protein suppressor of hairless isoform X4

UniProtKB/TrEMBL

A0A8V0Y6L7

Related

ENSGALP00010014593.1, ENSGALT00010025926.1

Conserved Domains (3) summary

cd01176
Location:337 → 433

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:193 → 315

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:35 → 160

LAG1-DNAbind; LAG1, DNA binding
XM_046940615.1 → XP_046796571.1 recombining binding protein suppressor of hairless isoform X3

UniProtKB/TrEMBL

A0A8V0Y6L7, A0A8V0Y8A1

Related

ENSGALP00010014626.1, ENSGALT00010025965.1
XM_046940617.1 → XP_046796573.1 recombining binding protein suppressor of hairless isoform X7

UniProtKB/TrEMBL

A0A8V0Y6L7, A0A8V0Y896

Related

ENSGALP00010014621.1, ENSGALT00010025957.1
XM_046940619.1 → XP_046796575.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_004936138.5 → XP_004936195.1 recombining binding protein suppressor of hairless isoform X2

UniProtKB/TrEMBL

A0A8V0Y210, A0A8V0Y6L7

Related

ENSGALP00010014614.1, ENSGALT00010025950.1

Conserved Domains (3) summary

cd01176
Location:348 → 444

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:204 → 326

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:46 → 171

LAG1-DNAbind; LAG1, DNA binding
XM_040699295.2 → XP_040555229.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

Conserved Domains (3) summary

cd01176
Location:315 → 411

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:171 → 293

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:13 → 138

LAG1-DNAbind; LAG1, DNA binding
XM_046940614.1 → XP_046796570.1 recombining binding protein suppressor of hairless isoform X1

UniProtKB/TrEMBL

A0A8V0Y206, A0A8V0Y6L7

Related

ENSGALP00010014609.1, ENSGALT00010025945.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

72729811..72874132 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046916871.1 → XP_046772827.1 recombining binding protein suppressor of hairless isoform X5

UniProtKB/TrEMBL

A0A8V0Y6Q4
XM_040670210.2 → XP_040526144.1 recombining binding protein suppressor of hairless isoform X6

UniProtKB/TrEMBL

A0A3Q2UCS9, A0A8V0Y6L7

Conserved Domains (3) summary

cd01176
Location:334 → 430

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:190 → 312

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:32 → 157

LAG1-DNAbind; LAG1, DNA binding
XM_046916873.1 → XP_046772829.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_046916875.1 → XP_046772831.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_040670209.2 → XP_040526143.1 recombining binding protein suppressor of hairless isoform X4

UniProtKB/TrEMBL

A0A8V0Y6L7

Conserved Domains (3) summary

cd01176
Location:337 → 433

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:193 → 315

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:35 → 160

LAG1-DNAbind; LAG1, DNA binding
XM_046916870.1 → XP_046772826.1 recombining binding protein suppressor of hairless isoform X3

UniProtKB/TrEMBL

A0A8V0Y6L7, A0A8V0Y8A1
XM_046916872.1 → XP_046772828.1 recombining binding protein suppressor of hairless isoform X7

UniProtKB/TrEMBL

A0A8V0Y6L7, A0A8V0Y896
XM_046916874.1 → XP_046772830.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8
XM_040670211.2 → XP_040526145.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

Conserved Domains (3) summary

cd01176
Location:315 → 411

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:171 → 293

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:13 → 138

LAG1-DNAbind; LAG1, DNA binding
XM_040670208.2 → XP_040526142.1 recombining binding protein suppressor of hairless isoform X9

UniProtKB/TrEMBL

A0A8V0Y6L7

Conserved Domains (1) summary

cd01176
Location:339 → 435

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
XM_040670207.2 → XP_040526141.1 recombining binding protein suppressor of hairless isoform X2

UniProtKB/TrEMBL

A0A8V0Y210, A0A8V0Y6L7

Conserved Domains (3) summary

cd01176
Location:348 → 444

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:204 → 326

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:46 → 171

LAG1-DNAbind; LAG1, DNA binding
XM_040670212.2 → XP_040526146.1 recombining binding protein suppressor of hairless isoform X8

UniProtKB/TrEMBL

A0A1D5PM75, A0A8V0Y6L7, F1NIJ8

Conserved Domains (3) summary

cd01176
Location:315 → 411

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:171 → 293

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:13 → 138

LAG1-DNAbind; LAG1, DNA binding
XM_046916869.1 → XP_046772825.1 recombining binding protein suppressor of hairless isoform X1

UniProtKB/TrEMBL

A0A8V0Y6L7