trip-4 TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: trip-4
Official Full Name: TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein
Primary source: WormBase:WBGene00000208
Locus tag: CELE_Y53F4B.15
See related: AllianceGenome:WB:WBGene00000208
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable zinc ion binding activity. Involved in dauer larval development. Predicted to be part of RQC-trigger complex. Predicted to be active in nucleus. Orthologous to human TRIP4 (thyroid hormone receptor interactor 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See trip-4 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (15039404..15048904)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y53F4B.s (e-PCR)
- UniSTS:324402

Y53F4B.r (e-PCR)
- UniSTS:323729

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in dauer larval development	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in rescue of stalled ribosome	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of RQC-trigger complex	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein

NP_497100.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

15039404..15048904

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064699.5 → NP_497100.1 TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497100.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EDK1

Conserved Domains (2) summary

pfam06221
Location:38 → 81

zf-C2HC5; Putative zinc finger motif, C2HC5-type

cl01020
Location:286 → 382

ASCH; ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, ...