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    • Showing Current items.

    F10E7.11 ELM2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174170, updated on 9-Dec-2024

    Summary

    Official Symbol
    F10E7.11
    Official Full Name
    ELM2 domain-containing protein
    Primary source
    WormBase:WBGene00017352
    Locus tag
    CELE_F10E7.11
    See related
    AllianceGenome:WB:WBGene00017352
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human MIER2 (MIER family member 2); MIER3 (MIER family member 3); and MIER1 (MIER1 transcriptional regulator). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F10E7.11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (7120517..7122892, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ribosome assembly factor mrt4 Neighboring gene Uncharacterized protein Neighboring gene ZP domain-containing protein Neighboring gene Spondin-1 Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene pseudo Neighboring gene ATP-dependent DNA helicase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables histone deacetylase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ELM2 domain-containing protein
    NP_001379868.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7120517..7122892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393115.1NP_001379868.1  ELM2 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19306
      Conserved Domains (2) summary
      cd11661
      Location:134177
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:2273
      ELM2; ELM2 domain