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    NIPBL NIPBL cohesin loading factor [ Gallus gallus (chicken) ]

    Gene ID: 427439, updated on 3-Dec-2024

    Summary

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    Official Symbol
    NIPBLprovided by CGNC
    Official Full Name
    NIPBL cohesin loading factorprovided by CGNC
    Primary source
    CGNC:53088
    See related
    Ensembl:ENSGALG00010013746
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See NIPBL in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    51
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (11847125..12006549)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (11847125..12006549)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 1 member 3 Neighboring gene uncharacterized LOC112530586 Neighboring gene U1 spliceosomal RNA Neighboring gene ciliogenesis and planar polarity effector 1 Neighboring gene nucleoporin 155 Neighboring gene WD repeat domain 70

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in digestive tract development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic viscerocranium morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of mitotic sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of protein localization to chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in replication-born double-strand break repair via sister chromatid exchange IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Scc2-Scc4 cohesin loading complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nipped-B-like protein
    Names
    Nipped-B homolog
    Nipped-B homolog-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11847125..12006549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046905814.1 → XP_046761770.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    2. XM_015277520.4 → XP_015133006.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66
      Conserved Domains (5) summary
      PTZ00121
      Location:469 → 1103
      PTZ00121; MAEBL; Provisional
      sd00044
      Location:1784 → 1812
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1767 → 1808
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:2253 → 2426
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1817 → 1851
      PDS5; HEAT repeat [structural motif]

    3. XM_040656537.2 → XP_040512471.1  nipped-B-like protein isoform X3

      UniProtKB/TrEMBL
      A0A1D5PVC0, A0A8V0YFB3
      Conserved Domains (5) summary
      sd00044
      Location:1573 → 1601
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1556 → 1597
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:2042 → 2215
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1606 → 1640
      PDS5; HEAT repeat [structural motif]
      NF033839
      Location:369 → 700
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form

    4. XM_046905815.1 → XP_046761771.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    5. XM_046905812.1 → XP_046761768.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    6. XM_046905813.1 → XP_046761769.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    7. XM_040656534.2 → XP_040512468.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66
      Related
      ENSGALP00010019509.1, ENSGALT00010033000.1
      Conserved Domains (5) summary
      PTZ00121
      Location:469 → 1103
      PTZ00121; MAEBL; Provisional
      sd00044
      Location:1784 → 1812
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1767 → 1808
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:2253 → 2426
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1817 → 1851
      PDS5; HEAT repeat [structural motif]

    8. XM_040656535.2 → XP_040512469.1  nipped-B-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8V0YFB3
      Related
      ENSGALP00010019526.1, ENSGALT00010033025.1
      Conserved Domains (5) summary
      PTZ00121
      Location:469 → 1103
      PTZ00121; MAEBL; Provisional
      sd00044
      Location:1784 → 1812
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1767 → 1808
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:2253 → 2426
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1817 → 1851
      PDS5; HEAT repeat [structural motif]

    9. XM_040656539.2 → XP_040512473.1  nipped-B-like protein isoform X4

      Conserved Domains (4) summary
      sd00044
      Location:1268 → 1296
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1251 → 1292
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:1737 → 1910
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1301 → 1335
      PDS5; HEAT repeat [structural motif]

    10. XM_040656536.2 → XP_040512470.1  nipped-B-like protein isoform X3

      UniProtKB/TrEMBL
      A0A1D5PVC0, A0A8V0YFB3
      Related
      ENSGALP00010019515.1, ENSGALT00010033010.1
      Conserved Domains (5) summary
      sd00044
      Location:1573 → 1601
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1556 → 1597
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:2042 → 2215
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1606 → 1640
      PDS5; HEAT repeat [structural motif]
      NF033839
      Location:369 → 700
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form

    11. XM_040656540.2 → XP_040512474.1  nipped-B-like protein isoform X5

      Conserved Domains (4) summary
      sd00044
      Location:1057 → 1085
      HEAT; HEAT repeat [structural motif]
      pfam12765
      Location:1040 → 1081
      Cohesin_HEAT; HEAT repeat associated with sister chromatid cohesion
      pfam12830
      Location:1526 → 1699
      Nipped-B_C; Sister chromatid cohesion C-terminus
      cd19953
      Location:1090 → 1124
      PDS5; HEAT repeat [structural motif]

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      11847125..12006549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046935481.1 → XP_046791437.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    2. XM_046935477.1 → XP_046791433.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    3. XM_046935485.1 → XP_046791441.1  nipped-B-like protein isoform X3

      UniProtKB/TrEMBL
      A0A1D5PVC0, A0A8V0YFB3

    4. XM_046935482.1 → XP_046791438.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    5. XM_046935478.1 → XP_046791434.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    6. XM_046935479.1 → XP_046791435.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    7. XM_046935480.1 → XP_046791436.1  nipped-B-like protein isoform X1

      UniProtKB/TrEMBL
      A0A182C6G1, A0A8V0YFB3, F1NJ66

    8. XM_046935483.1 → XP_046791439.1  nipped-B-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8V0YFB3

    9. XM_046935486.1 → XP_046791442.1  nipped-B-like protein isoform X4

    10. XM_046935484.1 → XP_046791440.1  nipped-B-like protein isoform X3

      UniProtKB/TrEMBL
      A0A1D5PVC0, A0A8V0YFB3

    11. XM_046935487.1 → XP_046791443.1  nipped-B-like protein isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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