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    WWC1 WW and C2 domain containing 1 [ Gallus gallus (chicken) ]

    Gene ID: 416167, updated on 3-Dec-2024

    Summary

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    Official Symbol
    WWC1provided by CGNC
    Official Full Name
    WW and C2 domain containing 1provided by CGNC
    Primary source
    CGNC:1284
    See related
    Ensembl:ENSGALG00010008135
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See WWC1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (4392447..4457418, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (4403806..4468885, complement)

    Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene rho GTPase-activating protein 7-like Neighboring gene microRNA 6569 Neighboring gene arginyl-tRNA synthetase Neighboring gene teneurin transmembrane protein 2 Neighboring gene uncharacterized LOC107054507 Neighboring gene methionine adenosyltransferase 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of hippo signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein KIBRA
    Names
    WW, C2 and coiled-coil domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277150.2 → NP_001264079.2  protein KIBRA

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000256
      UniProtKB/TrEMBL
      A0A8V0XRX3, A0A8V0XW90
      Related
      ENSGALP00010010954.1, ENSGALT00010019406.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4392447..4457418 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040646883.2 → XP_040502817.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90
      Conserved Domains (2) summary
      cd08680
      Location:567 → 690
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:66 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_040646882.2 → XP_040502816.1  protein KIBRA isoform X2

      UniProtKB/TrEMBL
      A0A8V0XW90
      Conserved Domains (3) summary
      cd08680
      Location:630 → 753
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:129 → 380
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00201
      Location:25 → 54
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

    3. XM_040646884.2 → XP_040502818.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90
      Conserved Domains (2) summary
      cd08680
      Location:567 → 690
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:66 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    4. XM_025154832.3 → XP_025010600.2  protein KIBRA isoform X1

      UniProtKB/TrEMBL
      A0A8V0XW90
      Conserved Domains (3) summary
      cd08680
      Location:635 → 758
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:134 → 385
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00201
      Location:30 → 59
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

    5. XM_040646885.2 → XP_040502819.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90
      Conserved Domains (2) summary
      cd08680
      Location:567 → 690
      C2_Kibra; C2 domain found in Human protein Kibra
      COG1196
      Location:66 → 317
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_046900334.1 → XP_046756290.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90
      Related
      ENSGALP00010010953.1, ENSGALT00010019405.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4403806..4468885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046926919.1 → XP_046782875.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90

    2. XM_046926917.1 → XP_046782873.1  protein KIBRA isoform X2

      UniProtKB/TrEMBL
      A0A8V0XW90

    3. XM_046926920.1 → XP_046782876.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90

    4. XM_046926916.1 → XP_046782872.1  protein KIBRA isoform X1

      UniProtKB/TrEMBL
      A0A8V0XW90

    5. XM_046926921.1 → XP_046782877.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90

    6. XM_046926918.1 → XP_046782874.1  protein KIBRA isoform X3

      UniProtKB/TrEMBL
      A0A8V0XW90
    Nucleotide Protein Strain
    Heading Accession and Version

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