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    POR cytochrome p450 oxidoreductase [ Gallus gallus (chicken) ]

    Gene ID: 417520, updated on 3-Dec-2024

    Summary

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    Symbol
    PORprovided by CGNC
    Full Name
    cytochrome p450 oxidoreductaseprovided by CGNC
    Primary source
    CGNC:1457
    See related
    Ensembl:ENSGALG00010029617
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CPR
    Orthologs
    human mouse all
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    Genomic context

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    See POR in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (4798317..4833179, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (4526726..4561598, complement)

    Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene malate dehydrogenase 2 Neighboring gene transmembrane protein 120A Neighboring gene rhomboid domain containing 2 Neighboring gene TATA-box binding protein associated factor 15 Neighboring gene matrix metallopeptidase 28 Neighboring gene growth arrest specific 2 like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NADPH-cytochrome P450 oxidoreductase from the chicken (Gallus gallus): sequence characterization, functional expression and kinetic study. Zhou X, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2011 Jan. PMID 20728568
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADPH-hemoprotein reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH--cytochrome P450 reductase
    Names
    P450 (cytochrome) oxidoreductase
    NP_001182725.2
    XP_015151204.2
    XP_015151205.2
    XP_046758290.1
    XP_046758291.1
    XP_046758292.1
    XP_046758293.1
    XP_046758294.1
    XP_046758295.1
    XP_046758296.1
    XP_046758297.1
    XP_046758298.1
    XP_046758300.1
    XP_046758301.1
    XP_046758302.1
    XP_046758303.1
    XP_046758304.1
    XP_046758305.1
    XP_046758306.1
    XP_046758307.1
    XP_046785966.1
    XP_046785967.1
    XP_046785968.1
    XP_046785969.1
    XP_046785970.1
    XP_046785971.1
    XP_046785972.1
    XP_046785973.1
    XP_046785974.1
    XP_046785975.1
    XP_046785976.1
    XP_046785977.1
    XP_046785978.1
    XP_046785979.1
    XP_046785980.1
    XP_046785981.1
    XP_046785982.1
    XP_046785983.1
    XP_046785984.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195796.2 → NP_001182725.2  NADPH--cytochrome P450 reductase

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000323
      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6
      Conserved Domains (2) summary
      cd06204
      Location:276 → 675
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      COG0716
      Location:72 → 225
      FldA; Flavodoxin [Energy production and conversion]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4798317..4833179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046902349.1 → XP_046758305.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    2. XM_046902348.1 → XP_046758304.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    3. XM_015295718.4 → XP_015151204.2  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6
      Related
      ENSGALP00010044302.1, ENSGALT00010071612.1
      Conserved Domains (2) summary
      cd06204
      Location:276 → 675
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      COG0716
      Location:72 → 225
      FldA; Flavodoxin [Energy production and conversion]

    4. XM_046902346.1 → XP_046758302.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6
      Related
      ENSGALP00010044304.1, ENSGALT00010071614.1

    5. XM_046902336.1 → XP_046758292.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    6. XM_046902345.1 → XP_046758301.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    7. XM_046902337.1 → XP_046758293.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    8. XM_046902339.1 → XP_046758295.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    9. XM_046902338.1 → XP_046758294.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    10. XM_046902340.1 → XP_046758296.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    11. XM_046902334.1 → XP_046758290.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    12. XM_046902341.1 → XP_046758297.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    13. XM_046902342.1 → XP_046758298.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    14. XM_046902344.1 → XP_046758300.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    15. XM_046902347.1 → XP_046758303.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    16. XM_046902335.1 → XP_046758291.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    17. XM_046902350.1 → XP_046758306.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    18. XM_046902351.1 → XP_046758307.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    19. XM_015295719.4 → XP_015151205.2  NADPH--cytochrome P450 reductase isoform X2

      UniProtKB/TrEMBL
      A0A8V1AE54, A0A8V1AN04
      Related
      ENSGALP00010044299.1, ENSGALT00010071609.1
      Conserved Domains (2) summary
      cd06204
      Location:233 → 632
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      COG0716
      Location:29 → 182
      FldA; Flavodoxin [Energy production and conversion]

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4526726..4561598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046930025.1 → XP_046785981.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    2. XM_046930024.1 → XP_046785980.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    3. XM_046930015.1 → XP_046785971.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    4. XM_046930022.1 → XP_046785978.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    5. XM_046930013.1 → XP_046785969.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    6. XM_046930021.1 → XP_046785977.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    7. XM_046930012.1 → XP_046785968.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    8. XM_046930016.1 → XP_046785972.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    9. XM_046930014.1 → XP_046785970.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    10. XM_046930017.1 → XP_046785973.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    11. XM_046930010.1 → XP_046785966.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    12. XM_046930018.1 → XP_046785974.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    13. XM_046930019.1 → XP_046785975.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    14. XM_046930020.1 → XP_046785976.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    15. XM_046930023.1 → XP_046785979.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    16. XM_046930011.1 → XP_046785967.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    17. XM_046930026.1 → XP_046785982.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    18. XM_046930028.1 → XP_046785984.1  NADPH--cytochrome P450 reductase isoform X1

      UniProtKB/TrEMBL
      A0A8V1APH9, E1AVU6

    19. XM_046930027.1 → XP_046785983.1  NADPH--cytochrome P450 reductase isoform X2

      UniProtKB/TrEMBL
      A0A8V1AE54
    Nucleotide Protein Strain
    Heading Accession and Version

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