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    SCUBE2 signal peptide, CUB domain and EGF like domain containing 2 [ Gallus gallus (chicken) ]

    Gene ID: 423049, updated on 3-Dec-2024

    Summary

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    Symbol
    SCUBE2provided by CGNC
    Full Name
    signal peptide, CUB domain and EGF like domain containing 2provided by CGNC
    Primary source
    CGNC:4399
    See related
    Ensembl:ENSGALG00010019483
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SCUBE2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (9158308..9196928)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (9125336..9165937)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418386 Neighboring gene transmembrane protein 41B Neighboring gene DENN domain containing 5A Neighboring gene nuclear receptor interacting protein 2 Neighboring gene uncharacterized LOC121110967

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Hubbard SJ, et al. Genome Res, 2005 Jan. PMID 15590942, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal peptide, CUB and EGF-like domain-containing protein 2
    Names
    signal peptide, CUB domain, EGF-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      9158308..9196928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015286474.4 → XP_015141960.4  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z3Z0

    2. XM_040701526.2 → XP_040557460.2  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z3Z0

    3. XM_015286477.4 → XP_015141963.4  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X6

    4. XM_015286475.4 → XP_015141961.4  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z3Z0

    5. XM_015286476.4 → XP_015141962.4  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z3Z0

    6. XM_420982.7 → XP_420982.4  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z3Z0, A0A8V0Z3Z9
      Related
      ENSGALP00010027947.1, ENSGALT00010047058.1
      Conserved Domains (3) summary
      smart00179
      Location:6 → 46
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:741 → 852
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:273 → 322
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RNA

    1. XR_005860192.2 RNA Sequence

    2. XR_001466551.4 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      9125336..9165937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040673553.2 → XP_040529487.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z3Z0
      Conserved Domains (3) summary
      smart00179
      Location:151 → 191
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:886 → 997
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:418 → 467
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    2. XM_040673554.2 → XP_040529488.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z3Z0
      Conserved Domains (3) summary
      smart00179
      Location:151 → 191
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:857 → 968
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:418 → 467
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    3. XM_040673558.2 → XP_040529492.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X6

      Conserved Domains (3) summary
      smart00179
      Location:151 → 191
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:731 → 842
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:418 → 467
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    4. XM_040673555.2 → XP_040529489.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z3Z0
      Conserved Domains (3) summary
      smart00179
      Location:151 → 191
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:844 → 955
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:376 → 425
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    5. XM_040673556.2 → XP_040529490.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z3Z0
      Conserved Domains (3) summary
      smart00179
      Location:151 → 191
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:886 → 997
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:418 → 467
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    6. XM_040673557.2 → XP_040529491.1  signal peptide, CUB and EGF-like domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z3Z0
      Conserved Domains (3) summary
      smart00179
      Location:6 → 46
      EGF_CA; Calcium-binding EGF-like domain
      cd00041
      Location:741 → 852
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00057
      Location:273 → 322
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RNA

    1. XR_005850797.2 RNA Sequence

    2. XR_005850796.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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