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    MTMR4 myotubularin related protein 4 [ Gallus gallus (chicken) ]

    Gene ID: 417472, updated on 3-Dec-2024

    Summary

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    Official Symbol
    MTMR4provided by CGNC
    Official Full Name
    myotubularin related protein 4provided by CGNC
    Primary source
    CGNC:705
    See related
    Ensembl:ENSGALG00010029602
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MTMR4 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (1137815..1181844, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (867657..911697, complement)

    Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 43 Neighboring gene translation initiation factor IF-2-like Neighboring gene heat shock transcription factor 5 Neighboring gene microRNA 1698-1 Neighboring gene caspase 1 Neighboring gene abhydrolase domain containing 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myotubularin-related protein 4
    XP_015151417.2
    XP_015151418.2
    XP_015151419.2
    XP_040506551.1
    XP_040543514.1
    XP_040543516.1
    XP_040543517.1
    XP_040543518.1
    XP_046758382.1
    XP_046786342.1
    XP_046786343.1
    XP_415720.6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1137815..1181844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_415720.7 → XP_415720.6  myotubularin-related protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:103 → 216
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1137 → 1196
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:254 → 561
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    2. XM_015295932.4 → XP_015151418.2  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Related
      ENSGALP00010044254.1, ENSGALT00010071564.1
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      pfam06602
      Location:159 → 521
      Myotub-related; Myotubularin-like phosphatase domain

    3. XM_015295931.4 → XP_015151417.2  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      pfam06602
      Location:159 → 521
      Myotub-related; Myotubularin-like phosphatase domain

    4. XM_015295933.4 → XP_015151419.2  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Related
      ENSGALP00010044252.1, ENSGALT00010071562.1
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      pfam06602
      Location:159 → 521
      Myotub-related; Myotubularin-like phosphatase domain

    5. XM_046902426.1 → XP_046758382.1  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Related
      ENSGALP00010044253.1, ENSGALT00010071563.1

    6. XM_040650617.2 → XP_040506551.1  myotubularin-related protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UI20, A0A8V1AJE0
      Related
      ENSGALP00010044251.1, ENSGALT00010071561.1
      Conserved Domains (3) summary
      cd13342
      Location:37 → 150
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1071 → 1130
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:188 → 495
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      867657..911697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040687580.1 → XP_040543514.1  myotubularin-related protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:103 → 216
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1137 → 1196
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:254 → 561
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    2. XM_040687583.2 → XP_040543517.1  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:174 → 481
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    3. XM_040687582.2 → XP_040543516.1  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:174 → 481
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    4. XM_040687584.2 → XP_040543518.1  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0
      Conserved Domains (3) summary
      cd13342
      Location:23 → 136
      PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      cd15733
      Location:1057 → 1116
      FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
      cd14587
      Location:174 → 481
      PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

    5. XM_046930387.1 → XP_046786343.1  myotubularin-related protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJE0

    6. XM_046930386.1 → XP_046786342.1  myotubularin-related protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8V1AJE0
    Nucleotide Protein Strain
    Heading Accession and Version

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