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    APH1B aph-1 homolog B, gamma-secretase subunit [ Gallus gallus (chicken) ]

    Gene ID: 769986, updated on 3-Dec-2024

    Summary

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    Official Symbol
    APH1Bprovided by CGNC
    Official Full Name
    aph-1 homolog B, gamma-secretase subunitprovided by CGNC
    Primary source
    CGNC:1855
    See related
    Ensembl:ENSGALG00010012290
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    APH1AL
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    Genomic context

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    See APH1B in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (9774350..9778942)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (9774350..9778942)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene tropomyosin 2 Neighboring gene uncharacterized LOC121108604 Neighboring gene carbonic anhydrase 9 Neighboring gene uncharacterized LOC107051926

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch receptor processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of gamma-secretase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-secretase subunit APH-1A; gamma-secretase subunit Aph-1b
    Names
    gamma-secretase subunit APH-1A-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      9774350..9778942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001233301.7 → XP_001233302.1  gamma-secretase subunit Aph-1b

      UniProtKB/TrEMBL
      A0A8V0YLV8
      Related
      ENSGALP00010017086.1, ENSGALT00010029415.1
      Conserved Domains (1) summary
      pfam06105
      Location:2 → 233
      Aph-1; Aph-1 protein

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      9774350..9778942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936333.1 → XP_046792289.1  gamma-secretase subunit Aph-1b

      UniProtKB/TrEMBL
      A0A8V0YLV8
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials