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    CPNE2 copine 2 [ Gallus gallus (chicken) ]

    Gene ID: 415646, updated on 3-Dec-2024

    Summary

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    Symbol
    CPNE2provided by CGNC
    Full Name
    copine 2provided by CGNC
    Primary source
    CGNC:50034
    See related
    Ensembl:ENSGALG00010022150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CPNE2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (647195..688182)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (777755..818730)

    Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene homocysteine inducible ER protein with ubiquitin like domain 1 Neighboring gene cholesteryl ester transfer protein Neighboring gene NLR family CARD domain containing 5 Neighboring gene uncharacterized LOC107054262 Neighboring gene family with sequence similarity 192 member A Neighboring gene glycine-rich RNA-binding protein 10-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    copine-2
    Names
    copine II

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278011.2 → NP_001264940.1  copine-2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000247
      UniProtKB/TrEMBL
      A0A8V0ZP37, E1BQ84
      Related
      ENSGALP00010032451.1, ENSGALT00010053895.1
      Conserved Domains (3) summary
      cd04047
      Location:151 → 262
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:20 → 137
      C2A_Copine; C2 domain first repeat in Copine
      pfam07002
      Location:322 → 539
      Copine; Copine

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      647195..688182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040707034.2 → XP_040562968.2  copine-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZP37

    2. XM_040707035.2 → XP_040562969.2  copine-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZLZ5, A0A8V0ZP37
      Related
      ENSGALP00010032465.1, ENSGALT00010053911.1

    3. XM_040707037.2 → XP_040562971.2  copine-2 isoform X6

    4. XM_046899403.1 → XP_046755359.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    5. XM_046899400.1 → XP_046755356.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    6. XM_046899404.1 → XP_046755360.1  copine-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZP37, E1BQ84
      Related
      ENSGALP00010032457.1, ENSGALT00010053902.1

    7. XM_015292298.4 → XP_015147784.2  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37
      Related
      ENSGALP00010032460.1, ENSGALT00010053906.1
      Conserved Domains (3) summary
      cd04047
      Location:151 → 262
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:20 → 137
      C2A_Copine; C2 domain first repeat in Copine
      cl00057
      Location:276 → 517
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    8. XM_046899402.1 → XP_046755358.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    9. XM_046899399.1 → XP_046755355.1  copine-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZP37

    10. XM_046899401.1 → XP_046755357.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      777755..818730
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046925406.1 → XP_046781362.1  copine-2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZP37

    2. XM_046925407.1 → XP_046781363.1  copine-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZLZ5, A0A8V0ZP37

    3. XM_046925415.1 → XP_046781371.1  copine-2 isoform X6

    4. XM_046925413.1 → XP_046781369.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    5. XM_046925410.1 → XP_046781366.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    6. XM_046925414.1 → XP_046781370.1  copine-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZP37, E1BQ84

    7. XM_046925409.1 → XP_046781365.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    8. XM_046925412.1 → XP_046781368.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    9. XM_046925408.1 → XP_046781364.1  copine-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZP37

    10. XM_046925411.1 → XP_046781367.1  copine-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZLZ0, A0A8V0ZP37

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012773.1: Suppressed sequence

      Description
      NM_001012773.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    2. NM_001257260.1: Suppressed sequence

      Description
      NM_001257260.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: NLRC5 (GeneID:84166).
    Nucleotide Protein Strain
    Heading Accession and Version

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