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    UNG uracil DNA glycosylase [ Gallus gallus (chicken) ]

    Gene ID: 374010, updated on 3-Dec-2024

    Summary

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    Symbol
    UNGprovided by CGNC
    Full Name
    uracil DNA glycosylaseprovided by CGNC
    Primary source
    CGNC:49003
    See related
    Ensembl:ENSGALG00010021483
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See UNG in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (6665723..6670040)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (6676305..6680623)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene SV2 related protein Neighboring gene ubiquitin specific peptidase 30 Neighboring gene alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Neighboring gene microRNA 6648-1 Neighboring gene acetyl-CoA carboxylase beta Neighboring gene forkhead box N4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Di Noia J, et al. Nature, 2002 Sep 5. PMID 12214226
    2. Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus. Chowdhury S, et al. FEBS Lett, 2013 Sep 17. PMID 23954625
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.
      Title: Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables uracil DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in base-excision repair, AP site formation via deaminated base removal IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uracil-DNA glycosylase
    NP_001385002.1
    NP_989520.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398073.1 → NP_001385002.1  uracil-DNA glycosylase isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000260
      UniProtKB/TrEMBL
      Q8AYC6

    2. NM_204189.2 → NP_989520.2  uracil-DNA glycosylase isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000260
      UniProtKB/TrEMBL
      F1NJG2, Q8AYC6
      Related
      ENSGALP00010031103.1, ENSGALT00010052091.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      6665723..6670040
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6676305..6680623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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