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    CEL carboxyl ester lipase [ Gallus gallus (chicken) ]

    Gene ID: 417165, updated on 3-Dec-2024

    Summary

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    Symbol
    CELprovided by CGNC
    Full Name
    carboxyl ester lipaseprovided by CGNC
    Primary source
    CGNC:2529
    See related
    Ensembl:ENSGALG00010028826
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CEL in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (7378545..7385460)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (6790097..6797073)

    Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene adenylate kinase 8 Neighboring gene sperm acrosome associated 9 Neighboring gene tuberous sclerosis 1 Neighboring gene growth factor independent 1B transcriptional repressor Neighboring gene uncharacterized LOC112529984 Neighboring gene general transcription factor IIIC subunit 5 Neighboring gene ral guanine nucleotide dissociation stimulator like 4 Neighboring gene uncharacterized LOC107052213

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association of a new 99-bp indel of the CEL gene promoter region with phenotypic traits in chickens. Wang X, et al. Sci Rep, 2020 Feb 21. PMID 32081917, Free PMC Article
    2. Tissue distribution of lipase genes related to triglyceride metabolism in laying hens (Gallus gallus). Sato K, et al. Comp Biochem Physiol B Biochem Mol Biol, 2010 Jan. PMID 19818411
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Association of a new 99-bp indel of the CEL gene promoter region with phenotypic traits in chickens.
      Title: Association of a new 99-bp indel of the CEL gene promoter region with phenotypic traits in chickens.
    2. Studies identify HTGL, EL, Lipase H, and CEL in a pre-mammalian species and reveals novel details about specific features of the expression of these important molecules in lipid metabolism.
      Title: Tissue distribution of lipase genes related to triglyceride metabolism in laying hens (Gallus gallus).
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables neurexin family protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sterol ester esterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triacylglycerol lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in postsynaptic membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in presynaptic membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic specialization membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bile salt-activated lipase
    Names
    carboxyl ester lipase (bile salt-stimulated lipase)
    NP_001013015.1
    XP_046757727.1
    XP_046784880.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012997.2 → NP_001013015.1  bile salt-activated lipase precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000308
      UniProtKB/TrEMBL
      A0A8V1ALS7
      Related
      ENSGALP00010042913.1, ENSGALT00010069729.1
      Conserved Domains (2) summary
      COG0657
      Location:117 → 237
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam00135
      Location:18 → 542
      COesterase; Carboxylesterase family

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      7378545..7385460
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046901771.1 → XP_046757727.1  bile salt-activated lipase isoform X1

      UniProtKB/TrEMBL
      A0A8V1ALS7

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      6790097..6797073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928924.1 → XP_046784880.1  bile salt-activated lipase isoform X1

      UniProtKB/TrEMBL
      A0A8V1ALS7
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials