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    ARHGAP25 Rho GTPase activating protein 25 [ Gallus gallus (chicken) ]

    Gene ID: 419516, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ARHGAP25provided by CGNC
    Official Full Name
    Rho GTPase activating protein 25provided by CGNC
    Primary source
    CGNC:66
    See related
    Ensembl:ENSGALG00010020323
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP25 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 22 NC_052553.1 (346723..363476, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 22 NC_052594.1 (360147..376900, complement)

    Chromosome 22 - NC_052553.1Genomic Context describing neighboring genes Neighboring gene gastrokine 3 Neighboring gene gastrokine 2 Neighboring gene bone morphogenetic protein 10 Neighboring gene uncharacterized LOC107054953 Neighboring gene CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 Neighboring gene proliferating cell nuclear antigen

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis, engulfment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in phagocytic cup IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030883.2 → NP_001026054.2  rho GTPase-activating protein 25

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000331
      UniProtKB/TrEMBL
      A0A1D5PK72, Q5ZJ53
      Related
      ENSGALP00010029018.1, ENSGALT00010049075.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052553.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      346723..363476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015297303.4 → XP_015152789.1  rho GTPase-activating protein 25 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDT5
      Related
      ENSGALP00010029012.1, ENSGALT00010049068.1
      Conserved Domains (4) summary
      cd04390
      Location:129 → 327
      RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
      cd13263
      Location:17 → 130
      PH_RhoGap25-like; Rho GTPase activating protein 25 and related proteins Pleckstrin homology (PH) domain
      pfam00169
      Location:19 → 123
      PH; PH domain
      cl23720
      Location:547 → 633
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    2. XM_046903356.1 → XP_046759312.1  rho GTPase-activating protein 25 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDT5

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052594.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      360147..376900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046931604.1 → XP_046787560.1  rho GTPase-activating protein 25 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDT5

    2. XM_046931603.1 → XP_046787559.1  rho GTPase-activating protein 25 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZDT5
    Nucleotide Protein Strain
    Heading Accession and Version

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