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    hmg-20 HMG box domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173124, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hmg-20
    Official Full Name
    HMG box domain-containing protein
    Primary source
    WormBase:WBGene00012209
    Locus tag
    CELE_W02D9.3
    See related
    AllianceGenome:WB:WBGene00012209
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to be active in nucleus. Is expressed in body wall musculature; head neurons; seam cell; ventral nerve cord; and vulval muscle. Orthologous to several human genes including HMG20A (high mobility group 20A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See hmg-20 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (12535314..12537671)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene DNA primase large subunit Neighboring gene Protein YIPF Neighboring gene Zf-3CxxC domain-containing protein Neighboring gene MATH domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MUT-14 and SMUT-1 DEAD box RNA helicases have overlapping roles in germline RNAi and endogenous siRNA formation. Phillips CM, et al. Curr Biol, 2014 Apr 14. PMID 24684932, Free PMC Article
    2. WormGender - Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement. Labocha MK, et al. PLoS One, 2015. PMID 26421844, Free PMC Article
    3. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
    4. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    HMG box domain-containing protein
    NP_493178.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12535314..12537671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060777.7 → NP_493178.1  HMG box domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493178.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVG8
      Conserved Domains (1) summary
      smart00398
      Location:126 → 193
      HMG; high mobility group
    Nucleotide Protein
    Heading Accession and Version

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