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    ADORA2A adenosine A2a receptor [ Gallus gallus (chicken) ]

    Gene ID: 427705, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADORA2Aprovided by CGNC
    Official Full Name
    adenosine A2a receptorprovided by CGNC
    Primary source
    CGNC:5013
    See related
    Ensembl:ENSGALG00010026448
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ADORA2A in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (8481619..8510505, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (8492369..8521227, complement)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein D3 polypeptide Neighboring gene guanylyl cyclase domain containing 1 Neighboring gene beta-ureidopropionase 1 Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like Neighboring gene BCR activator of RhoGEF and GTPase Neighboring gene RAB36, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of A1 adenosine receptors in the developing avian retina: in vivo modulation by A(2A) receptors and endogenous adenosine. Brito R, et al. J Neurochem, 2012 Oct. PMID 22862679
    2. Modulation of A1 adenosine receptor expression by cell aggregation and long-term activation of A2a receptors in cultures of avian retinal cells: involvement of the cyclic AMP/PKA pathway. Pereira MR, et al. J Neurochem, 2010 May. PMID 20163523
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long-term treatment with A2A adenosine receptors in developing retina modulate expression of A1 adenosine receptors.
      Title: Expression of A1 adenosine receptors in the developing avian retina: in vivo modulation by A(2A) receptors and endogenous adenosine.
    2. adenosine A2a receptor and the cAMP-dependent protein kinase pathway are involved in the regulation of adenosine A1 receptor expression during retinal development
      Title: Modulation of A1 adenosine receptor expression by cell aggregation and long-term activation of A2a receptors in cultures of avian retinal cells: involvement of the cyclic AMP/PKA pathway.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled adenosine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled adenosine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenosine receptor A2a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      8481619..8510505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040648132.2 → XP_040504066.1  adenosine receptor A2a isoform X1

      UniProtKB/TrEMBL
      A0A8V1ADB5
      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_040648131.2 → XP_040504065.1  adenosine receptor A2a isoform X1

      UniProtKB/TrEMBL
      A0A8V1ADB5
      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_040648130.2 → XP_040504064.1  adenosine receptor A2a isoform X1

      UniProtKB/TrEMBL
      A0A8V1ADB5
      Related
      ENSGALP00010039497.1, ENSGALT00010064309.1
      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. XM_046901333.1 → XP_046757289.1  adenosine receptor A2a isoform X2

    RNA

    1. XR_005840036.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      8492369..8521227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040684943.2 → XP_040540877.1  adenosine receptor A2a isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_040684942.2 → XP_040540876.1  adenosine receptor A2a isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_040684941.2 → XP_040540875.1  adenosine receptor A2a isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:14 → 40
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:13 → 308
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. XM_046928480.1 → XP_046784436.1  adenosine receptor A2a isoform X2

    RNA

    1. XR_005854444.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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