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    NTN4 netrin 4 [ Gallus gallus (chicken) ]

    Gene ID: 417914, updated on 3-Dec-2024

    Summary

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    Symbol
    NTN4provided by CGNC
    Full Name
    netrin 4provided by CGNC
    Primary source
    CGNC:8669
    See related
    Ensembl:ENSGALG00010011859
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    netrin-4
    Orthologs
    human mouse all
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    Genomic context

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    See NTN4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (45649593..45685920, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (46001132..46037460, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene methionyl aminopeptidase 2 Neighboring gene ubiquitin specific peptidase 44 Neighboring gene small nuclear ribonucleoprotein polypeptide F Neighboring gene amidohydrolase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in basement membrane assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of laminin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    netrin-4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      45649593..45685920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015283916.4 → XP_015139402.2  netrin-4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJJ8
      Conserved Domains (4) summary
      smart00180
      Location:393 → 444
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:259 → 318
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:514 → 624
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:30 → 258
      Laminin_N; Laminin N-terminal (Domain VI)

    2. XM_004937645.5 → XP_004937702.3  netrin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6F0, A0A8V0YJJ8
      Related
      ENSGALP00010016230.1, ENSGALT00010028328.1
      Conserved Domains (4) summary
      smart00180
      Location:393 → 444
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:259 → 318
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:515 → 625
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:30 → 258
      Laminin_N; Laminin N-terminal (Domain VI)

    3. XM_046909072.1 → XP_046765028.1  netrin-4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJJ8

    4. XM_004937647.5 → XP_004937704.3  netrin-4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y6E6, A0A8V0YJJ8
      Related
      ENSGALP00010016225.1, ENSGALT00010028323.1
      Conserved Domains (4) summary
      smart00180
      Location:383 → 434
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:249 → 308
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:505 → 615
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:20 → 248
      Laminin_N; Laminin N-terminal (Domain VI)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      46001132..46037460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040660028.2 → XP_040515962.1  netrin-4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJJ8
      Conserved Domains (4) summary
      smart00180
      Location:393 → 444
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:259 → 318
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:514 → 624
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:30 → 258
      Laminin_N; Laminin N-terminal (Domain VI)

    2. XM_040660027.2 → XP_040515961.1  netrin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y6F0, A0A8V0YJJ8
      Conserved Domains (4) summary
      smart00180
      Location:393 → 444
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:259 → 318
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:515 → 625
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:30 → 258
      Laminin_N; Laminin N-terminal (Domain VI)

    3. XM_046909474.1 → XP_046765430.1  netrin-4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJJ8

    4. XM_040660029.2 → XP_040515963.1  netrin-4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y6E6, A0A8V0YJJ8
      Conserved Domains (4) summary
      smart00180
      Location:383 → 434
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      cd00055
      Location:249 → 308
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd03578
      Location:505 → 615
      NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
      cl02806
      Location:20 → 248
      Laminin_N; Laminin N-terminal (Domain VI)
    Nucleotide Protein
    Heading Accession and Version

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