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    SORBS2 sorbin and SH3 domain containing 2 [ Gallus gallus (chicken) ]

    Gene ID: 422719, updated on 3-Dec-2024

    Summary

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    Symbol
    SORBS2provided by CGNC
    Full Name
    sorbin and SH3 domain containing 2provided by CGNC
    Primary source
    CGNC:10100
    See related
    Ensembl:ENSGALG00010017094
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    9430041O17RIK
    Orthologs
    human mouse all
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    Genomic context

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    See SORBS2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (60615336..60758158, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (60613370..60756728, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 110 Neighboring gene PDZ and LIM domain 3 Neighboring gene uncharacterized LOC112532411 Neighboring gene family with sequence similarity 149 member A Neighboring gene toll like receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sorbin and SH3 domain-containing protein 2
    Names
    Arg/Abl-interacting protein ArgBP2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      60615336..60758158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040699935.2 → XP_040555869.1  sorbin and SH3 domain-containing protein 2 isoform X7

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      smart00459
      Location:251 → 301
      Sorb; Sorbin homologous domain
      cd11917
      Location:1287 → 1347
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1076 → 1130
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1151 → 1207
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)

    2. XM_046940863.1 → XP_046796819.1  sorbin and SH3 domain-containing protein 2 isoform X3

    3. XM_046940865.1 → XP_046796821.1  sorbin and SH3 domain-containing protein 2 isoform X5

    4. XM_040699934.2 → XP_040555868.1  sorbin and SH3 domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z6P7
      Related
      ENSGALP00010024166.1, ENSGALT00010041276.1
      Conserved Domains (4) summary
      smart00459
      Location:328 → 378
      Sorb; Sorbin homologous domain
      cd11917
      Location:1364 → 1424
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1153 → 1207
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1228 → 1284
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)

    5. XM_046940861.1 → XP_046796817.1  sorbin and SH3 domain-containing protein 2 isoform X2

    6. XM_040699950.2 → XP_040555884.1  sorbin and SH3 domain-containing protein 2 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YT14
      Related
      ENSGALP00010024185.1, ENSGALT00010041300.1
      Conserved Domains (4) summary
      smart00459
      Location:148 → 198
      Sorb; Sorbin homologous domain
      cd11917
      Location:594 → 654
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:494 → 550
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:419 → 473
      SH3; Src Homology 3 domain superfamily

    7. XM_040699940.2 → XP_040555874.1  sorbin and SH3 domain-containing protein 2 isoform X8

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      smart00459
      Location:148 → 198
      Sorb; Sorbin homologous domain
      cd11917
      Location:1184 → 1244
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1048 → 1104
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:973 → 1027
      SH3; Src Homology 3 domain superfamily

    8. XM_046940864.1 → XP_046796820.1  sorbin and SH3 domain-containing protein 2 isoform X4

    9. XM_040699941.2 → XP_040555875.1  sorbin and SH3 domain-containing protein 2 isoform X9

      UniProtKB/TrEMBL
      E1BSP7
      Related
      ENSGALP00010024175.1, ENSGALT00010041288.1
      Conserved Domains (4) summary
      smart00459
      Location:139 → 189
      Sorb; Sorbin homologous domain
      cd11917
      Location:1175 → 1235
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1039 → 1095
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:964 → 1018
      SH3; Src Homology 3 domain superfamily

    10. XM_046940866.1 → XP_046796822.1  sorbin and SH3 domain-containing protein 2 isoform X5

    11. XM_046940862.1 → XP_046796818.1  sorbin and SH3 domain-containing protein 2 isoform X2

    12. XM_046940860.1 → XP_046796816.1  sorbin and SH3 domain-containing protein 2 isoform X1

    13. XM_004935983.5 → XP_004936040.1  sorbin and SH3 domain-containing protein 2 isoform X11

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      cd11917
      Location:942 → 1002
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:842 → 898
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:8 → 30
      Sorb; Sorbin homologous domain
      cl17036
      Location:767 → 821
      SH3; Src Homology 3 domain superfamily

    14. XM_004935986.5 → XP_004936043.1  sorbin and SH3 domain-containing protein 2 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Z155
      Conserved Domains (3) summary
      cd11923
      Location:332 → 388
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:8 → 33
      Sorb; Sorbin homologous domain
      cl17036
      Location:432 → 492
      SH3; Src Homology 3 domain superfamily

    15. XM_046940867.1 → XP_046796823.1  sorbin and SH3 domain-containing protein 2 isoform X10

      UniProtKB/TrEMBL
      E1BSP7

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      60613370..60756728 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040671272.2 → XP_040527206.1  sorbin and SH3 domain-containing protein 2 isoform X7

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      smart00459
      Location:251 → 301
      Sorb; Sorbin homologous domain
      cd11917
      Location:1287 → 1347
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1076 → 1130
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1151 → 1207
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)

    2. XM_046917114.1 → XP_046773070.1  sorbin and SH3 domain-containing protein 2 isoform X3

    3. XM_046917116.1 → XP_046773072.1  sorbin and SH3 domain-containing protein 2 isoform X5

    4. XM_040671271.2 → XP_040527205.1  sorbin and SH3 domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z6P7
      Conserved Domains (4) summary
      smart00459
      Location:328 → 378
      Sorb; Sorbin homologous domain
      cd11917
      Location:1364 → 1424
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1153 → 1207
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1228 → 1284
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)

    5. XM_046917112.1 → XP_046773068.1  sorbin and SH3 domain-containing protein 2 isoform X2

    6. XM_040671294.2 → XP_040527228.1  sorbin and SH3 domain-containing protein 2 isoform X12

      UniProtKB/TrEMBL
      A0A8V0YT14
      Conserved Domains (4) summary
      smart00459
      Location:148 → 198
      Sorb; Sorbin homologous domain
      cd11917
      Location:594 → 654
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:494 → 550
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:419 → 473
      SH3; Src Homology 3 domain superfamily

    7. XM_040671278.2 → XP_040527212.1  sorbin and SH3 domain-containing protein 2 isoform X8

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      smart00459
      Location:148 → 198
      Sorb; Sorbin homologous domain
      cd11917
      Location:1184 → 1244
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1048 → 1104
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:973 → 1027
      SH3; Src Homology 3 domain superfamily

    8. XM_046917115.1 → XP_046773071.1  sorbin and SH3 domain-containing protein 2 isoform X4

    9. XM_040671280.2 → XP_040527214.1  sorbin and SH3 domain-containing protein 2 isoform X9

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      smart00459
      Location:139 → 189
      Sorb; Sorbin homologous domain
      cd11917
      Location:1175 → 1235
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1039 → 1095
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl17036
      Location:964 → 1018
      SH3; Src Homology 3 domain superfamily

    10. XM_046917117.1 → XP_046773073.1  sorbin and SH3 domain-containing protein 2 isoform X5

    11. XM_046917113.1 → XP_046773069.1  sorbin and SH3 domain-containing protein 2 isoform X2

    12. XM_046917111.1 → XP_046773067.1  sorbin and SH3 domain-containing protein 2 isoform X1

    13. XM_040671283.2 → XP_040527217.1  sorbin and SH3 domain-containing protein 2 isoform X11

      UniProtKB/TrEMBL
      E1BSP7
      Conserved Domains (4) summary
      cd11917
      Location:942 → 1002
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:842 → 898
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:8 → 30
      Sorb; Sorbin homologous domain
      cl17036
      Location:767 → 821
      SH3; Src Homology 3 domain superfamily

    14. XM_040671295.2 → XP_040527229.1  sorbin and SH3 domain-containing protein 2 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Z155
      Conserved Domains (3) summary
      cd11923
      Location:332 → 388
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cl02617
      Location:8 → 33
      Sorb; Sorbin homologous domain
      cl17036
      Location:432 → 492
      SH3; Src Homology 3 domain superfamily

    15. XM_046917118.1 → XP_046773074.1  sorbin and SH3 domain-containing protein 2 isoform X10

      UniProtKB/TrEMBL
      E1BSP7
    Nucleotide Protein Strain
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