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    phm-2 Pharyngeal muscle protein 2 [ Caenorhabditis elegans ]

    Gene ID: 185193, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phm-2
    Official Full Name
    Pharyngeal muscle protein 2
    Primary source
    WormBase:WBGene00009314
    Locus tag
    CELE_F32B4.4
    See related
    AllianceGenome:WB:WBGene00009314
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of mRNA processing and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including body wall musculature; intestine; pharynx; somatic nervous system; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See phm-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (11517558..11526797)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Nucleotide-diphospho-sugar transferase domain-containing protein Neighboring gene Peroxisome biogenesis protein 3-2-like Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene HSF_DOMAIN domain-containing protein;Zeta_toxin domain-containing protein Neighboring gene ncRNA Neighboring gene Dystrophin;Dystrophin-1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans is a model host for Salmonella typhimurium. Labrousse A, et al. Curr Biol, 2000 Nov 30. PMID 11114526
    2. Caenorhabditis elegans: plague bacteria biofilm blocks food intake. Darby C, et al. Nature, 2002 May 16. PMID 12015591
    3. A liquid-based method for the assessment of bacterial pathogenicity using the nematode Caenorhabditis elegans. Smith MP, et al. FEMS Microbiol Lett, 2002 May 7. PMID 12044672
    4. Killing of Caenorhabditis elegans by Burkholderia cepacia is controlled by the cep quorum-sensing system. Köthe M, et al. Cell Microbiol, 2003 May. PMID 12713492
    5. Live and dead GFP-tagged bacteria showed indistinguishable fluorescence in Caenorhabditis elegans gut. Hsiao JY, et al. J Microbiol, 2013 Jun. PMID 23812817

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in digestion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pharyngeal muscle protein 2
    NP_001021440.2
    • Confirmed by transcript evidence
    NP_001251667.1
    • Confirmed by transcript evidence
    NP_001379397.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11517558..11526797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026269.4 → NP_001021440.2  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021440.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F5GUF6, O62203, Q7Z0X2
      Conserved Domains (2) summary
      smart00513
      Location:9 → 43
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd12417
      Location:397 → 474
      RRM_SAFB_like; RNA recognition motif (RRM) found in the scaffold attachment factor (SAFB) family

    2. NM_001392949.1 → NP_001379397.1  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cl17169
      Location:4 → 64
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. NM_001264738.3 → NP_001251667.1  Pharyngeal muscle protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251667.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F5GUF6
      Conserved Domains (1) summary
      cd12417
      Location:326 → 403
      RRM_SAFB_like; RNA recognition motif in the scaffold attachment factor (SAFB) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O62203.3

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