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    cgt-1 Ceramide glucosyltransferase 1 [ Caenorhabditis elegans ]

    Gene ID: 188169, updated on 9-Dec-2024

    Summary

    Official Symbol
    cgt-1
    Official Full Name
    Ceramide glucosyltransferase 1
    Primary source
    WormBase:WBGene00011517
    Locus tag
    CELE_T06C12.10
    See related
    AllianceGenome:WB:WBGene00011517
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ceramide glucosyltransferase activity. Involved in glucosylceramide biosynthetic process; nematode larval development; and regulation of protein localization to basolateral plasma membrane. Predicted to be active in membrane. Is expressed in excretory system; intestine; pharyngeal muscle cell; pharyngeal-intestinal valve; and rectum. Orthologous to human UGCG (UDP-glucose ceramide glucosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cgt-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (15886719..15888851, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Acyl_transf_3 domain-containing protein;Acyltransferase 3 domain-containing protein Neighboring gene Plasma membrane proteolipid 3 Neighboring gene Movement protein Neighboring gene Seven TM Receptor

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ceramide glucosyltransferase activity  
    enables ceramide glucosyltransferase activity  
    enables glycosyltransferase activity  
    Component Evidence Code Pubs
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    Ceramide glucosyltransferase 1
    NP_506971.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15886719..15888851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074570.6 → NP_506971.2  Ceramide glucosyltransferase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506971.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O18037
      Conserved Domains (2) summary
      TIGR03472
      Location:68 → 446
      HpnI; hopanoid biosynthesis associated glycosyl transferase protein HpnI
      cd02520
      Location:107 → 338
      Glucosylceramide_synthase; Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis
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