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    T22B7.7 HotDog ACOT-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180832, updated on 9-Dec-2024

    Summary

    Official Symbol
    T22B7.7
    Official Full Name
    HotDog ACOT-type domain-containing protein
    Primary source
    WormBase:WBGene00020674
    Locus tag
    CELE_T22B7.7
    See related
    AllianceGenome:WB:WBGene00020674
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Predicted to be active in mitochondrion. Orthologous to human ACOT9 (acyl-CoA thioesterase 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See T22B7.7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (5651865..5654074, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene SGF29 C-terminal domain-containing protein Neighboring gene Serpentine Receptor, class V Neighboring gene Amidinotransferase Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    HotDog ACOT-type domain-containing protein
    NP_001362037.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5651865..5654074 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001375037.3NP_001362037.1  HotDog ACOT-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23044
      Conserved Domains (2) summary
      PLN02647
      Location:58367
      PLN02647; acyl-CoA thioesterase
      cd03442
      Location:250374
      BFIT_BACH; Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis, ...