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    F10G8.1 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

    Gene ID: 184322, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F10G8.1
    Official Full Name
    Protein-tyrosine phosphatase
    Primary source
    WormBase:WBGene00008661
    Locus tag
    CELE_F10G8.1
    See related
    AllianceGenome:WB:WBGene00008661
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Orthologous to human PTPN7 (protein tyrosine phosphatase non-receptor type 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F10G8.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (10019643..10021090)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Collagen triple helix repeat protein Neighboring gene Anti-proliferative protein domain-containing protein Neighboring gene Protein kinase domain-containing protein Neighboring gene Tyrosine-protein phosphatase non-receptor type eak-6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase
    NP_001251277.1
    • Confirmed by transcript evidence
    NP_001380118.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10019643..10021090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001264348.3 → NP_001251277.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251277.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G8JZG5
      Conserved Domains (2) summary
      cd00047
      Location:82 → 317
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:83 → 317
      Y_phosphatase; Protein-tyrosine phosphatase

    2. NM_001392924.1 → NP_001380118.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      I2HAD7
      Conserved Domains (1) summary
      cl28904
      Location:1 → 80
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
    Nucleotide Protein
    Heading Accession and Version

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