U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    his-34 Histone H2B 1 [ Caenorhabditis elegans ]

    Gene ID: 191679, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    his-34
    Official Full Name
    Histone H2B 1
    Primary source
    WormBase:WBGene00001908
    Locus tag
    CELE_F17E9.9
    See related
    AllianceGenome:WB:WBGene00001908
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC12 (H2B clustered histone 12); and H2BC17 (H2B clustered histone 17). [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See his-34 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (8335972..8336340)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene Histone H2A Neighboring gene pseudo Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Evidence for dynamic alteration in histone gene clusters of Caenorhabditis elegans: a topoisomerase II connection? Holt SJ, et al. Genet Res, 2002 Feb. PMID 11974600
    2. Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B. Liu Y, et al. Structure, 2019 Dec 3. PMID 31653339
    3. The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Pettitt J, et al. J Cell Sci, 2002 Feb 15. PMID 11865041
    4. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Histone H2B 1
    NP_501409.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8335972..8336340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069008.1 → NP_501409.1  Histone H2B 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501409.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02656, P04255
      Conserved Domains (1) summary
      smart00427
      Location:24 → 120
      H2B; Histone H2B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P04255.4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials