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    AHC2 Ahc2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850443, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AHC2
    Official Full Name
    Ahc2p
    Primary source
    SGD:S000000678
    Locus tag
    YCR082W
    See related
    AllianceGenome:SGD:S000000678; FungiDB:YCR082W; VEuPathDB:YCR082W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of ADA complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AHC2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (258883..259269)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene type 2C protein phosphatase PTC6 Neighboring gene Srb8p Neighboring gene Trx3p Neighboring gene chromatin-silencing transcriptional regulator TUP1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional activators in yeast. Titz B, et al. Nucleic Acids Res, 2006. PMID 16464826, Free PMC Article
    2. Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. Eustice M, et al. Genetics, 2014 Apr. PMID 24532730, Free PMC Article
    3. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Poli J, et al. Genes Dev, 2016 Feb 1. PMID 26798134, Free PMC Article
    4. Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles. Decourty L, et al. Proc Natl Acad Sci U S A, 2008 Apr 15. PMID 18408161, Free PMC Article
    5. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables transcription regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ADA complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of ADA complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ahc2p
    NP_010005.1
    • Component of the ADA histone acetyltransferase complex; Ahc2p and Ahc1p are unique to the ADA complex and not shared with the related SAGA and SLIK complexes; may tether Ahc1p to the complex

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      258883..259269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178788.1 → NP_010005.1  TPA: Ahc2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010005.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR83, P25649
      UniProtKB/TrEMBL
      A6ZTQ4, B3LUD6, C7GUW6, C8Z4G9, G2WA90, N1P972
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25649.1

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