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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855695, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000004980
    Locus tag
    YNL035C
    See related
    AllianceGenome:SGD:S000004980; FungiDB:YNL035C; VEuPathDB:YNL035C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in cytosol and nucleus. Orthologous to human WDR89 (WD repeat domain 89). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (568522..569691, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene tRNA-Pro Neighboring gene tRNA-Ile Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Balakrishnan R, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608219, Free PMC Article
    2. Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Brachat A, et al. Yeast, 2000 Feb. PMID 10649453
    3. Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae. Zou J, et al. Mol Biol Cell, 2009 Jul. PMID 19458192, Free PMC Article
    4. The Rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast. Imbeault D, et al. J Biol Chem, 2008 Oct 10. PMID 18708354
    5. The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Dastidar RG, et al. Cell Biosci, 2012 Aug 29. PMID 22932476, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_014363.1
    • Nuclear hypothetical protein; relocalizes to the cytosol in response to hypoxia; contains WD-40 domains; not an essential gene; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      568522..569691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182874.1 → NP_014363.1  TPA: uncharacterized protein YNL035C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014363.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1E4, P53962
      UniProtKB/TrEMBL
      G2WM68, N1NZK8
      Conserved Domains (2) summary
      sd00039
      Location:59 → 98
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:17 → 212
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53962.1

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