U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    ncx-3 Calx-beta domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177963, updated on 27-Dec-2024

    Summary

    Official Symbol
    ncx-3
    Official Full Name
    Calx-beta domain-containing protein
    Primary source
    WormBase:WBGene00003568
    Locus tag
    CELE_ZC168.1
    See related
    AllianceGenome:WB:WBGene00003568
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in calcium ion import across plasma membrane and sodium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in axon; postsynapse; and sarcolemma. Is expressed in dorsal nerve cord; head neurons; phasmid neurons; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ncx-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    9
    Sequence:
    Chromosome: IV; NC_003282.8 (10716648..10721755)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene MARVEL domain-containing protein Neighboring gene RING-type domain-containing protein Neighboring gene Globin domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Origin recognition complex subunit 5 C-terminal domain-containing protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables antiporter activity  
    enables calcium:sodium antiporter activity  
    enables calcium:sodium antiporter activity  
    enables calmodulin binding  
    enables metal ion binding  
    Process Evidence Code Pubs
    involved_in calcium ion import across plasma membrane  
    involved_in calcium ion transport  
    involved_in cell communication  
    involved_in sodium ion transmembrane transport  
    involved_in sodium ion transport  
    involved_in transmembrane transport  
    Component Evidence Code Pubs
    is_active_in axon  
    located_in membrane  
    located_in plasma membrane  
    is_active_in postsynapse  
    is_active_in sarcolemma  

    General protein information

    Preferred Names
    Calx-beta domain-containing protein
    NP_501984.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10716648..10721755
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069583.4NP_501984.2  Calx-beta domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501984.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECW0
      Conserved Domains (5) summary
      smart00237
      Location:470559
      Calx_beta; Domains in Na-Ca exchangers and integrin-beta4
      TIGR00845
      Location:8825
      caca; sodium/calcium exchanger 1
      pfam01699
      Location:659822
      Na_Ca_ex; Sodium/calcium exchanger protein
      pfam05823
      Location:216297
      Gp-FAR-1; Nematode fatty acid retinoid binding protein (Gp-FAR-1)
      cl02522
      Location:348435
      Calx-beta; Calx-beta domain
    External link. Please review our privacy policy.