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    arrd-6 Arrestin C-terminal-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185541, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arrd-6
    Official Full Name
    Arrestin C-terminal-like domain-containing protein
    Primary source
    WormBase:WBGene00009579
    Locus tag
    CELE_F40F8.8
    See related
    AllianceGenome:WB:WBGene00009579
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein transport. Predicted to be active in cytoplasm. Is expressed in amphid process; head ganglion; nerve ring; tail neurons; and ventral nerve cord. Orthologous to human TXNIP (thioredoxin interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See arrd-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (11142897..11150390)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Expressed conserved protein;Filaggrin-like;Secreted protein Neighboring gene Fatty-acid and retinol-binding protein 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Zinc finger transcription factor pqm-1 Neighboring gene tRNA-Lys Neighboring gene SSD domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structures of the TMC-1 complex illuminate mechanosensory transduction. Jeong H, et al. Nature, 2022 Oct. PMID 36224384, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Arrestin C-terminal-like domain-containing protein
    NP_001254290.1
    • Confirmed by transcript evidence
    NP_001254291.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11142897..11150390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267361.3 → NP_001254290.1  Arrestin C-terminal-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D1MN74
      Conserved Domains (2) summary
      smart01017
      Location:201 → 336
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:34 → 174
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. NM_001267362.2 → NP_001254291.1  Arrestin C-terminal-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254291.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20232
      Conserved Domains (2) summary
      smart01017
      Location:174 → 309
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:7 → 147
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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