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    unc-46 Lysosome-associated membrane glycoprotein 5 [ Caenorhabditis elegans ]

    Gene ID: 178897, updated on 9-Dec-2024

    Summary

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    Official Symbol
    unc-46
    Official Full Name
    Lysosome-associated membrane glycoprotein 5
    Primary source
    WormBase:WBGene00006782
    Locus tag
    CELE_C04F5.3
    See related
    AllianceGenome:WB:WBGene00006782
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in cytoplasmic vesicle and neuromuscular junction. Is expressed in GLR and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See unc-46 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (5097075..5099025, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene G protein-coupled receptor;Serpentine Receptor, class E (Epsilon) Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Serpentine Receptor, class AB (class A-like)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pairing for recombination in LGV of Caenorhabditis elegans: a model based on recombination in deficiency heterozygotes. Rosenbluth RE, et al. Genetics, 1990 Mar. PMID 2311918, Free PMC Article
    2. Photoaged microplastics induce neurotoxicity associated with damage to serotonergic, glutamatergic, dopaminergic, and GABAergic neuronal systems in Caenorhabditis elegans. Yu Y, et al. Sci Total Environ, 2023 Nov 20. PMID 37517734
    3. Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation. Tarailo-Graovac M, et al. BMC Genomics, 2015 Mar 18. PMID 25880765, Free PMC Article
    4. The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo. Mello CC, et al. Cell, 1994 Apr 8. PMID 8156602
    5. Neurotoxicological evaluation of microcystin-LR exposure at environmental relevant concentrations on nematode Caenorhabditis elegans. Ju J, et al. Environ Sci Pollut Res Int, 2013 Mar. PMID 22956115

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Lysosome-associated membrane glycoprotein 5
    NP_504365.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5097075..5099025 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071964.5 → NP_504365.1  Lysosome-associated membrane glycoprotein 5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504365.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GZD5
    Nucleotide Protein
    Heading Accession and Version

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