mboa-1 O-acyltransferase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: mboa-1
Official Full Name: O-acyltransferase
Primary source: WormBase:WBGene00007174
Locus tag: CELE_B0395.2
See related: AllianceGenome:WB:WBGene00007174
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable O-acyltransferase activity. Predicted to be involved in cholesterol metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in head; nervous system; reproductive system; seam cell; and tail. Human ortholog(s) of this gene implicated in Chagas disease; coronary artery disease; and hepatocellular carcinoma. Orthologous to several human genes including SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables O-acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables cholesterol O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables sterol O-acyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cholesterol homeostasis	IEA Inferred from Electronic Annotation more info
involved_in cholesterol metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cholesterol metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_510623.1

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The following sections contain reference sequences that belong to a specific genome build. Explain