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    rei-2 Guanine nucleotide exchange factor rei-2 [ Caenorhabditis elegans ]

    Gene ID: 180461, updated on 2-Nov-2024

    Summary

    Official Symbol
    rei-2
    Official Full Name
    Guanine nucleotide exchange factor rei-2
    Primary source
    WormBase:WBGene00019365
    Locus tag
    CELE_K03E6.7
    See related
    AllianceGenome:WB:WBGene00019365
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human SH3BP5L (SH3 binding domain protein 5 like) and SH3BP5 (SH3 domain binding protein 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See rei-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (1084217..1088148, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene B9 domain-containing protein 1 Neighboring gene LIM/homeobox protein lim-6 Neighboring gene Profilin-3 Neighboring gene tRNA-Arg Neighboring gene tRNA-Arg Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Guanine nucleotide exchange factor rei-2
    NP_508206.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1084217..1088148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075805.6NP_508206.2  Guanine nucleotide exchange factor rei-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508206.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21194
      Conserved Domains (1) summary
      pfam05276
      Location:33259
      SH3BP5; SH3 domain-binding protein 5 (SH3BP5)