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    T28D6.4 ANK_REP_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176566, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T28D6.4
    Official Full Name
    ANK_REP_REGION domain-containing protein
    Primary source
    WormBase:WBGene00012124
    Locus tag
    CELE_T28D6.4
    See related
    AllianceGenome:WB:WBGene00012124
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein localization to ciliary inversin compartment. Predicted to be active in cilium. Is expressed in body wall musculature; intestinal muscle; nervous system; and reproductive system. Orthologous to human ANKRD50 (ankyrin repeat domain containing 50). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T28D6.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (11360456..11366198)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA-Val Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cystatin domain-containing protein Neighboring gene Tubulin alpha chain Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein localization to ciliary inversin compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ANK_REP_REGION domain-containing protein
    NP_499461.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11360456..11366198
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067060.8 → NP_499461.1  ANK_REP_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18152
      Conserved Domains (3) summary
      PHA03095
      Location:507 → 776
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:594 → 624
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:428 → 521
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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