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    trmt-10C.2 tRNA MethylTransferase [ Caenorhabditis elegans ]

    Gene ID: 183866, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trmt-10C.2
    Official Full Name
    tRNA MethylTransferase
    Primary source
    WormBase:WBGene00016978
    Locus tag
    CELE_C56G2.3
    See related
    AllianceGenome:WB:WBGene00016978
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to be active in mitochondrion and nucleoplasm. Is expressed in body wall musculature; intestine; nervous system; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trmt-10C.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (6346281..6348410)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Proteasomal ubiquitin receptor ADRM1;Proteasomal ubiquitin receptor ADRM1 homolog Neighboring gene DUF4604 domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene KH domain-containing protein akap-1;Tudor domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans. Chen TY, et al. Aging Cell, 2024 Apr. PMID 38361361, Free PMC Article
    2. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial tRNA 5'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA MethylTransferase
    NP_001367605.1
    • Confirmed by transcript evidence;
      Product from WormBase gene class trmt

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6346281..6348410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379760.2 → NP_001367605.1  tRNA MethylTransferase [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cl38912
      Location:186 → 367
      SPOUT_MTase; SPOUT superfamily of SAM-dependent RNA methyltransferases
    Nucleotide Protein
    Heading Accession and Version

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