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    R05G6.4 Nitric oxide synthase-interacting protein homolog [ Caenorhabditis elegans ]

    Gene ID: 177526, updated on 9-Dec-2024

    Summary

    Official Symbol
    R05G6.4
    Official Full Name
    Nitric oxide synthase-interacting protein homolog
    Primary source
    WormBase:WBGene00019898
    Locus tag
    CELE_R05G6.4
    See related
    AllianceGenome:WB:WBGene00019898
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human NOSIP (nitric oxide synthase interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See R05G6.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (7513233..7514407)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uroporphyrinogen-III synthase Neighboring gene Phosphoinositide phospholipase C Neighboring gene ncRNA Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene Venom peptide

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm  
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    Nitric oxide synthase-interacting protein homolog
    NP_501214.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7513233..7514407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068813.10 → NP_501214.1  Nitric oxide synthase-interacting protein homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501214.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21755
      Conserved Domains (2) summary
      pfam15906
      Location:4 → 78
      zf-NOSIP; Zinc-finger of nitric oxide synthase-interacting protein
      cl17238
      Location:190 → 285
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
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