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    CG7611 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40386, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7611provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037094
    Locus tag
    Dmel_CG7611
    See related
    AllianceGenome:FB:FBgn0037094
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7611; WDR26
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of GID complex. Is expressed in adult head and organism. Orthologous to human WDR26 (WD repeat domain 26). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7611 in Genome Data Viewer
    Location:
    78D5-78D5; 3-47 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21523186..21528163)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21516286..21521263)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene M6 Neighboring gene Sak kinase Neighboring gene Cyclin-dependent kinase 12 Neighboring gene antisense RNA:CR43877 Neighboring gene ACAT-related protein required for viability 1 Neighboring gene Makorin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition. Zavortink M, et al. Elife, 2020 Jun 23. PMID 32573431, Free PMC Article
    2. mTORC1-chaperonin CCT signaling regulates m(6)A RNA methylation to suppress autophagy. Tang HW, et al. Proc Natl Acad Sci U S A, 2021 Mar 9. PMID 33649236, Free PMC Article
    3. dCas9-targeted locus-specific protein isolation method identifies histone gene regulators. Tsui C, et al. Proc Natl Acad Sci U S A, 2018 Mar 20. PMID 29507191, Free PMC Article
    4. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cao WX, et al. Cell Rep, 2020 Jun 23. PMID 32579915, Free PMC Article
    5. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Finan D, et al. Proc Natl Acad Sci U S A, 2011 Apr 5. PMID 21368190, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of GID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of GID complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7611-PA
    CG7611-PB
    CG7611-PC
    CG7611-PD
    CG7611-PE
    CG7611-PG
    CG7611-PH
    CG7611-PI
    CG7611-PJ

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21523186..21528163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001170018.2 → NP_001163489.1  uncharacterized protein Dmel_CG7611, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163489.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_141069.4 → NP_649326.1  uncharacterized protein Dmel_CG7611, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649326.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078022
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_168918.3 → NP_730649.1  uncharacterized protein Dmel_CG7611, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730649.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078017
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. NM_168913.3 → NP_730644.1  uncharacterized protein Dmel_CG7611, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730644.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078018
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. NM_168915.3 → NP_730646.1  uncharacterized protein Dmel_CG7611, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730646.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078021
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    6. NM_168914.3 → NP_730645.1  uncharacterized protein Dmel_CG7611, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730645.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078020
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    7. NM_168919.3 → NP_730650.1  uncharacterized protein Dmel_CG7611, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730650.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078019
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    8. NM_168917.3 → NP_730648.1  uncharacterized protein Dmel_CG7611, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730648.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0290416
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    9. NM_168916.3 → NP_730647.1  uncharacterized protein Dmel_CG7611, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730647.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V292, Q7K0L4
      UniProtKB/TrEMBL
      E1JHX5
      Related
      FBpp0078015
      Conserved Domains (4) summary
      smart00668
      Location:129 → 190
      CTLH; C-terminal to LisH motif
      COG2319
      Location:303 → 605
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:318 → 358
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:307 → 602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JHX5 E1JHX5
    Q7K0L4.1 Q7K0L4

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