TfIIA-L Transcription factor IIA L [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: TfIIA-Lprovided by FlyBase
Official Full Name: Transcription factor IIA Lprovided by FlyBase
Primary source: FLYBASE:FBgn0011289
Locus tag: Dmel_CG5930
See related: AllianceGenome:FB:FBgn0011289
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5930; CT18631; Dmel\CG5930; dTFIIA; TfIIA; TFIIA; tfiia-l; TFIIA-L; TFIIAL
Summary: Enables TBP-class protein binding activity and TFIID-class transcription factor complex binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in nucleus. Part of transcription factor TFIIA complex. Is expressed in organism. Orthologous to several human genes including GTF2A1 (general transcription factor IIA subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (27251112..27256463)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (23076834..23082185)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	IPI Inferred from Physical Interaction more info	PubMed
enables TBP-class protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables TFIID-class transcription factor complex binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info
involved_in transcription initiation at RNA polymerase II promoter	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of transcription factor TFIIA complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIA complex	IDA Inferred from Direct Assay more info	PubMed
part_of transcription factor TFIIA complex	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIA complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain