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    ImpE1 Ecdysone-inducible gene E1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 45879, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ImpE1provided by FlyBase
    Official Full Name
    Ecdysone-inducible gene E1provided by FlyBase
    Primary source
    FLYBASE:FBgn0001253
    Locus tag
    Dmel_CG32356
    See related
    AllianceGenome:FB:FBgn0001253
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE39082; CG13668; CG32356; CG7116; CT22003; CT33103; Dmel\CG32356; Imp-E1; IMP-E1
    Summary
    Predicted to be involved in imaginal disc eversion. Predicted to be extrinsic component of membrane. Is expressed in several structures, including embryonic head epidermis; embryonic ventral epidermis; epithelium; gut section; and hindgut proper primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ImpE1 in Genome Data Viewer
    Location:
    66C8-66C10; 3-24 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8372405..8391171)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8365505..8384271)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene mir-4913 stem loop Neighboring gene CUB and LDLa domain Neighboring gene Isocitrate dehydrogenase Neighboring gene Jonah 66Ci Neighboring gene Jonah 66Cii

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parallel molecular genetic pathways operate during CNS metamorphosis in Drosophila. Restifo LL, et al. Mol Cell Neurosci, 1998 Jun. PMID 9647692
    2. Genes expressed during imaginal disc morphogenesis: IMP-E1, a gene associated with epithelial cell rearrangement. Natzle JE, et al. Dev Biol, 1988 Oct. PMID 2458289
    3. Temporal regulation of Drosophila imaginal disc morphogenesis: a hierarchy of primary and secondary 20-hydroxyecdysone-responsive loci. Natzle JE. Dev Biol, 1993 Feb. PMID 8432403
    4. Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone. Petryk A, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610274, Free PMC Article
    5. Metamorphosis in drosophila and other insects: the fate of neurons throughout the stages. Tissot M, et al. Prog Neurobiol, 2000 Sep. PMID 10821983

    See all (66) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in imaginal disc eversion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ecdysone-inducible gene E1
    Names
    CG32356-PA
    CG32356-PB
    CG32356-PC
    ImpE1-PA
    ImpE1-PB
    ImpE1-PC
    Y1-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8372405..8391171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274648.1 → NP_001261577.1  Ecdysone-inducible gene E1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261577.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUB3, Q9VSI9, Q9VSJ0
      Conserved Domains (2) summary
      cd00112
      Location:1404 → 1437
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam01683
      Location:75 → 131
      EB; EB module

    2. NM_080110.3 → NP_524849.2  Ecdysone-inducible gene E1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524849.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUB3, Q9VSI9, Q9VSJ0
      Related
      FBpp0076333
      Conserved Domains (2) summary
      cd00112
      Location:1404 → 1437
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      pfam01683
      Location:75 → 131
      EB; EB module

    3. NM_168270.2 → NP_729371.1  Ecdysone-inducible gene E1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729371.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SWT9
      Related
      FBpp0076334
      Conserved Domains (1) summary
      pfam01683
      Location:75 → 131
      EB; EB module
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KUB3 Q7KUB3
    Q8SWT9 Q8SWT9
    Q9VSJ0 Q9VSJ0

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