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    cdi center divider [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42289, updated on 9-Dec-2024

    Summary

    Official Symbol
    cdiprovided by FlyBase
    Official Full Name
    center dividerprovided by FlyBase
    Primary source
    FLYBASE:FBgn0004876
    Locus tag
    Dmel_CG6027
    See related
    AllianceGenome:FB:FBgn0004876
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    91F; B9.3; Cdi; cdi/TESK1; Cdi/TESK1; CDI/TSKI; CG6027; Dmel\CG6027; l(3)07013
    Summary
    Predicted to enable protein serine/threonine kinase activity. Involved in actin filament organization and negative regulation of sevenless signaling pathway. Located in apical part of cell and cytosol. Is expressed in several structures, including embryonic/larval epidermis; eye photoreceptor cell; eye-antennal disc; gut section; and male germline cell. Orthologous to human TESK1 (testis associated actin remodelling kinase 1) and TESK2 (testis associated actin remodelling kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cdi in Genome Data Viewer
    Location:
    91E4-91F1; 3-65 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19044882..19094270, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14870604..14919992, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46041 Neighboring gene ATP synthase, subunit D Neighboring gene mitochondrial ribosomal protein L55

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding  
    enables protein kinase activity  
    enables protein serine/threonine kinase activity  
    Component Evidence Code Pubs
    located_in apical part of cell PubMed 
    is_active_in cytoplasm  
    located_in cytosol PubMed 
    is_active_in nucleus  

    General protein information

    Preferred Names
    center divider
    Names
    91F gene
    CG6027-PA
    CG6027-PB
    cdi-PA
    cdi-PB
    central divider
    centre divider
    centrer divider
    NP_001247191.1
    NP_524401.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19044882..19094270 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260262.2 → NP_001247191.1  center divider, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247191.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K689
      Conserved Domains (2) summary
      smart00219
      Location:113 → 362
      TyrKc; Tyrosine kinase, catalytic domain
      cl21453
      Location:116 → 369
      PKc_like; Protein Kinases, catalytic domain
    2. NM_079677.4 → NP_524401.2  center divider, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524401.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE06, Q9Y1A8
      Related
      FBpp0083130
      Conserved Domains (2) summary
      smart00219
      Location:113 → 363
      TyrKc; Tyrosine kinase, catalytic domain
      cl21453
      Location:116 → 370
      PKc_like; Protein Kinases, catalytic domain
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