spok spookier [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: spokprovided by FlyBase
Official Full Name: spookierprovided by FlyBase
Primary source: FLYBASE:FBgn0086917
Locus tag: Dmel_CG41624
See related: AllianceGenome:FB:FBgn0086917
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 307a2p; CG40123; CG41624; cyp307a2; Cyp307a2; CYP307A2; Cyp307a2p; Cyp307a2Psi; Dmel\CG41624; Dmspok; spo2; Spok
Summary: Predicted to enable heme binding activity and oxidoreductase activity. Involved in ecdysone biosynthetic process and molting cycle. Is expressed in prothoracic gland. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (3322810..3354486)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3RHet	NW_001848858.1 (2127079..2158789, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Study indicates that the expression of spookier in the ecdysteroid biosynthesis pathway requires ouib protein in dorsophila. [review]
Title: Ouija board: A transcription factor evolved for only one target in steroid hormone biosynthesis in the fruit fly Drosophila melanogaster.
These observations imply that the main biological function of Ouib is to specifically regulate spookier transcription during Drosophila development.
Title: The Drosophila Zinc Finger Transcription Factor Ouija Board Controls Ecdysteroid Biosynthesis through Specific Regulation of spookier.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info
enables heme binding	ISM Inferred from Sequence Model more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	ISM Inferred from Sequence Model more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ecdysone biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in molting cycle, chitin-based cuticle	IMP Inferred from Mutant Phenotype more info	PubMed