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    Mys45A Mystery 45A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35925, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mys45Aprovided by FlyBase
    Official Full Name
    Mystery 45Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033379
    Locus tag
    Dmel_CG8070
    See related
    AllianceGenome:FB:FBgn0033379
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.170; CG8070; Dmel\CG8070; Mys-45A; Mys45a
    Summary
    Predicted to be involved in ribosomal large subunit biogenesis and ribosomal large subunit export from nucleus. Predicted to be active in nucleolus. Is expressed in adult head; organism; and spermatozoon. Orthologous to human SDAD1 (SDA1 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Mys45A in Genome Data Viewer
    Location:
    45A7-45A8; 2-60 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9111505..9113951, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4999010..5001456, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Van Gogh Neighboring gene Phosphoglucomutase 2a Neighboring gene tsunagi Neighboring gene Phosphorylated adaptor for RNA export Neighboring gene Suppressor of variegation 2-10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis. Mohr SE, et al. Genes Dev, 2001 Nov 1. PMID 11691839, Free PMC Article
    2. Spatial regulation of microRNA gene expression in the Drosophila embryo. Biemar F, et al. Proc Natl Acad Sci U S A, 2005 Nov 1. PMID 16249329, Free PMC Article
    3. Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Okamura K, et al. Nat Struct Mol Biol, 2008 Jun. PMID 18500351, Free PMC Article
    4. Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Roignant JY, et al. Cell, 2010 Oct 15. PMID 20946982, Free PMC Article
    5. Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. Azad P, et al. G3 (Bethesda), 2012 Oct. PMID 23050227, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mystery 45A
    Names
    CG8070-PA
    Mys45A-PA
    mystery

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      9111505..9113951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136611.4 → NP_610455.1  mystery 45A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610455.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7KKH3
      Related
      FBpp0087709
      Conserved Domains (2) summary
      pfam05285
      Location:409 → 711
      SDA1; SDA1
      pfam08158
      Location:62 → 111
      NUC130_3NT; NUC130/3NT domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KKH3.1 Q7KKH3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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